Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529783 | 0.92 | L3MBTL1 (0.35) | L3MBTL1AOC3BCHETDP1GAA | |
| SCHEMBL2529932 | 0.89 | L3MBTL1 (0.36) | L3MBTL1AOC3BCHEELANEBACE1 | |
| SCHEMBL2528951 | 0.86 | L3MBTL1 (0.42) | L3MBTL1AOC3TDP1ELANE | |
| SCHEMBL2529691 | 0.84 | ALDH1A1 (0.41) | L3MBTL1AOC3TDP1GAA | |
| SCHEMBL2527806 | 0.84 | MEN1 (0.40) | L3MBTL1AOC3TDP1GAA | |
| SCHEMBL2526481 | 0.84 | L3MBTL1 (0.38) | L3MBTL1AOC3BCHETDP1ELANE | |
| SCHEMBL2531907 | 0.84 | TAAR1 (0.42) | L3MBTL1GAABACE1 | |
| SCHEMBL2529934 | 0.83 | BACE1 (0.33) | BACE1 | |
| SCHEMBL2532057 | 0.82 | CA2 (0.40) | L3MBTL1SIRT5AOC3BCHETDP1 | |
| SCHEMBL2525471 | 0.82 | ALDH1A1 (0.38) | L3MBTL1SIRT5AOC3TDP1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | L3MBTL1 4486/4885SIRT5 181/4885AOC3 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.