Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 4/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 0.77 |
| ▸ | RET | P07949 | 1/20 | 0.77 |
| ▸ | KDR | P35968 | 1/20 | 0.77 |
| ▸ | KDM5A | P29375 | 1/20 | 0.77 |
| ▸ | TERT | O14746 | 1/20 | 0.74 |
| ▸ | CREB1 | P16220 | 1/20 | 0.74 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | ABL1 | P00519 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974548 | 1.00 | MAPT (1.00) | MAPTABCB1EGFRRETKDR | |
| SCHEMBL5792042 | 0.95 | MAPT (0.91) | MAPTABCB1EGFRRETKDR | |
| SCHEMBL14048682 | 0.88 | MAPT (0.78) | MAPTABCB1EGFRRETKDR | |
| SCHEMBL10025658 | 0.87 | MAPT (0.77) | MAPTABCB1EGFRRETKDR | |
| SCHEMBL7306849 | 0.85 | MAPT (0.74) | MAPTABCB1EGFRRETKDR | |
| SCHEMBL8305040 | 0.85 | MAPT (0.73) | MAPTABCB1EGFRRETKDR | |
| SCHEMBL24882669 | 0.85 | EGFR (0.78) | MAPTABCB1EGFRRETKDR | |
| SCHEMBL28031602 | 0.85 | EGFR (0.74) | MAPTABCB1EGFRRETKDR | |
| SCHEMBL971995 | 0.85 | CREB1 (1.00) | MAPTABCB1EGFRRETKDR | |
| SCHEMBL19267888 | 0.84 | L3MBTL1 (0.77) | MAPTABCB1EGFRRETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111836808-B | Novel compound for preventing, alleviating or treating fibrosis or nonalcoholic steatohepatitis and composition comprising the same as active ingredient | 欧斯特奥纽罗根有限公司 | 2023-04-28 | — | — | CN | disclosed |