SCHEMBL253033

SCHEMBL253033

CCOCCCOC=C(C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
THRB P10828 1/20 0.35
KDM4E B2RXH2 4/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CES2 O00748 1/20 0.32
POLB P06746 1/20 0.32
HTT P42858 2/20 0.32
KMT2A Q03164 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3082202 0.89 ALDH1A1 (0.47) ALDH1A1TSHRTHRBHPGDNPC1
SCHEMBL809306 0.82 ALDH1A1 (0.45) ALDH1A1TSHRTHRBHPGDCES2
SCHEMBL809305 0.82 ALDH1A1 (0.45) ALDH1A1TSHRTHRBHPGDCES2
Ether SCHEMBL29157255 0.81 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL898727 0.81 HCAR2 (0.43) ALDH1A1TSHRTHRBCES2
SCHEMBL898728 0.81 HCAR2 (0.43) ALDH1A1TSHRTHRBCES2
SCHEMBL28370469 0.81 ALDH1A1 (0.43) ALDH1A1TSHRTHRBHPGDCES2
SCHEMBL28506569 0.80 PTGS1 (0.33) KDM4ESMN1; SMN2TDP1L3MBTL1
SCHEMBL3388405 0.79 CES2 (0.46) ALDH1A1TSHRTHRBCES2
SCHEMBL28126163 0.79 CES2 (0.46) ALDH1A1TSHRTHRBCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968090-B1 METHOD OF REMOVING POLYMERIZED COATINGS FROM HUMAN NAILS, POLYMERIZED COATING FOR HUMAN NAILS HAVING IMPROVED REMOVABILITY, AND TWO PACKAGE SYSTEM MYCONE DENTAL SUPPLY COMPANY INC (US) 2021-06-02 EP disclosed
EP-2525773-B1 EASILY APPLIABLE, STORAGE STABLE, RADIATION-CURABLE, PIGMENTED, ARTIFICIAL NAIL GEL COATINGS MYCONE DENTAL SUPPLY CO INC (US) 2020-02-12 EP disclosed
EP-2547730-B1 METHOD OF PREPARATION OF RADIATION-CURABLE COLORED ARTIFICIAL NAIL GELS MYCONE DENTAL SUPPLY COMPANY INC (US) 2019-07-10 EP disclosed
US-20190151222-A1 ONE PART ARTIFICIAL NAIL SCULPTING COMPOSITIONS AND METHODS WITHOUT REACTIVE OLIGOMERS NAIL ALLIANCE, LLC 2019-05-23 US disclosed
US-20190151223-A1 ONE PART ARTIFICIAL NAIL COMPOSITIONS MYCONE DENTAL SUPPLY CO INC (US) 2019-05-23 US disclosed
US-20190125652-A1 One Part Acrylic Nail Formulation MYCONE DENTAL SUPPLY CO INC (US) 2019-05-02 US disclosed
EP-3471831-A1 ONE PART ACRYLIC NAIL FORMULATION Mycone Dental Supply Company, Inc. (US) 2019-04-24 EP disclosed
EP-2363109-B1 Uv-curable nail coating formulations based on renewable polyols MYCONE DENTAL SUPPLY COMPANY INC (US) 2018-09-05 EP disclosed
US-20180092827-A1 ONE PART ACRYLIC NAIL FORMULATION WITH DISCONTINUOUS PHASE MYCONE DENTAL SUPPLY CO INC (US) 2018-04-05 US disclosed
US-9931284-B2 Method of removing polymerized coatings for human nails, polymerized coating for human nails having improved removability, and two package system MYCONE DENTAL SUPPLY COMPANY, INC. (US) 2018-04-03 US disclosed
EP-2547730-A2 METHOD OF PREPARATION OF RADIATION-CURABLE COLORED ARTIFICIAL NAIL GELS Mycone Dental Supply Company Inc. (US) 2013-01-23 EP disclosed
US-20120252710-A1 METHOD AND COMPOSITION FOR REMOVING RADIATION-CURABLE, PIGMENTED, ARTIFICIAL NAIL GEL COATINGS MYCONE DENTAL SUPPLY CO., INC. (US) 2012-10-04 US disclosed
US-20120004340-A1 METHOD OF PREPARATION OF RADIATION-CURABLE COLORED ARTIFICIAL NAIL GELS MYCONE DENTAL SUPPLY COMPANY, INC. (US) 2012-01-05 US disclosed
WO-2011130362-A2 EASILY APPLIABLE, STORAGE STABLE, RADIATION-CURABLE, PIGMENTED, ARTIFICIAL NAIL GEL COATINGS MYCONE DENTAL SUPPLY CO., INC. (US) 2011-10-20 WO disclosed
US-20110256079-A1 Easily appliable, storage stable, radiation-curable, pigmented, artificial nail gel coatings MYCONE DENTAL CORPORATION 2011-10-20 US disclosed
US-20110256080-A1 Easily appliable, storage stable, radiation-curable, pigmented, artificial nail gel coatings MYCONE DENTAL CORPORATION 2011-10-20 US disclosed
US-20110226271-A1 Method of Preparation of Radiation-Curable Colored Artificial Nail Gels MYCONE DENTAL SUPPLY COMPANY, INC. (US) 2011-09-22 US disclosed
WO-2011115795-A2 METHOD OF PREPARATION OF RADIATION-CURABLE COLORED ARTIFICIAL NAIL GELS MYCONE DENTAL SUPPLY COMPANY, INC. (US) 2011-09-22 WO disclosed
EP-2363109-A2 Uv-curable nail coating formulations based on renewable polyols Mycone Dental Supply Company, Inc. (US) 2011-09-07 EP disclosed
US-20110182837-A1 UV-CURABLE NAIL COATING FORMULATIONS BASED ON RENEWABLE POLYOLS MYCONE DENTAL SUPPLY CO., INC. (US) 2011-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190151223-A1 ONE PART ARTIFICIAL NAIL COMPOSITIONS POLR1C, PIK3C3, NACA ALDH1A1 3782/4885TSHR 1716/4885THRB 1902/4885
US-20190151222-A1 ONE PART ARTIFICIAL NAIL SCULPTING COMPOSITIONS AND METHODS WITHOUT REACTIVE OLIGOMERS POLR1C, NACA, SUCLG1 ALDH1A1 2608/4885TSHR 1396/4885THRB 732/4885
US-20180092827-A1 ONE PART ACRYLIC NAIL FORMULATION WITH DISCONTINUOUS PHASE POLR1C, NACA, PIK3C3 ALDH1A1 2055/4885TSHR 1748/4885THRB 853/4885
US-20190125652-A1 One Part Acrylic Nail Formulation POLR1C, NACA, PIK3C3 ALDH1A1 321/4885TSHR 3359/4885THRB 2500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.