SCHEMBL26124046

SCHEMBL26124046

CC(C)(C)OC(=O)N1CC(c2cncnc2N2CCC2)C1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 8/20 0.45
▸ PDE10A Q9Y233 1/20 0.43
▸ CKS1B P61024 1/20 0.41
▸ SKP1 P63208 1/20 0.41
▸ SKP2 Q13309 1/20 0.41
▸ KIT P10721 2/20 0.41
▸ IDO1 P14902 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ PIK3R1 P27986 1/20 0.38
▸ PIK3CA P42336 1/20 0.38
▸ ALOX5AP P20292 1/20 0.38
▸ FEN1 P39748 1/20 0.38
▸ HPGDS O60760 1/20 0.38
▸ HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30599815 1.00 GPR119 (0.45) GPR119PDE10ACKS1BSKP1SKP2
SCHEMBL26669576 0.86 GPR119 (0.50) GPR119CKS1BSKP1SKP2KIT
SCHEMBL25888707 0.83 GPR119 (0.43) GPR119IDO1KDM4EPIK3CAALOX5AP
SCHEMBL25307351 0.81 GPR119 (0.41) GPR119IDO1KDM4EPIK3CA
SCHEMBL30527693 0.81 GPR119 (0.41) GPR119IDO1KDM4EPIK3CA
SCHEMBL25306591 0.80 JAK1 (0.44) GPR119IDO1KDM4EALOX5APFEN1
SCHEMBL2798741 0.75 KIT (0.51) GPR119CKS1BSKP1SKP2KIT
SCHEMBL31654522 0.75 GPR119 (0.47) GPR119PDE10AKDM4EHPGDSHPGD
SCHEMBL10319563 0.75 GPR119 (0.53) GPR119CKS1BSKP1SKP2KIT
SCHEMBL25888855 0.75 GPR119 (0.47) GPR119PDE10AKDM4EHPGDSHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215030-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 — — US disclosed
EP-4499656-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2025-02-05 — — EP disclosed
WO-2023192960-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-10-05 — — WO disclosed
WO-2023192960-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-10-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215030-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A GPR119 386/4885PDE10A 1098/4885CKS1B 849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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