SCHEMBL25307602

SCHEMBL25307602

CC(Cc1ccc(C(F)(F)F)cc1Cl)[C@@H](N)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 11/20 0.45
▸ FFAR1 O14842 1/20 0.44
▸ PDE2A O00408 1/20 0.44
▸ MRGPRX4 Q96LA9 1/20 0.41
▸ DPP7 Q9UHL4 2/20 0.41
▸ ACACB O00763 1/20 0.40
▸ TRPV1 Q8NER1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2900363 0.83 GRB2 (0.52) MC4RFFAR1PDE2AMRGPRX4
SCHEMBL2900362 0.83 GRB2 (0.52) MC4RFFAR1PDE2AMRGPRX4
SCHEMBL18682189 0.77 PDE2A (0.53) MC4RFFAR1PDE2AMRGPRX4ACACB
SCHEMBL5300296 0.72 GRB2 (0.52) FFAR1
SCHEMBL29718989 0.72 RXRA (0.50) FFAR1PDE2AMRGPRX4
SCHEMBL838070 0.72 RXRA (0.50) FFAR1PDE2AMRGPRX4
SCHEMBL2669965 0.71 DAO (0.51) PDE2AMRGPRX4
SCHEMBL31434971 0.71 DAO (0.46) MC4RPDE2AMRGPRX4
SCHEMBL4007916 0.70 FFAR1 (0.58) FFAR1MRGPRX4
Trifluoroacetic Acid SCHEMBL5769358 0.69 FFAR1 (0.47) FFAR1PDE2AMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463438-B1 IMPROVED PROCESS OPTIMIZATION IN PRODUCTION OF AN INSECTICIDAL SUBSTANCE IN INDUSTRIAL SCALE ADAMA MAKHTESHIM LTD (IL) 2026-01-07 — — EP disclosed
US-20250091985-A1 IMPROVED PROCESS OPTIMIZATION IN PRODUCTION OF AN INSECTICIDAL SUBSTANCE IN INDUSTRIAL SCALE ADAMA MAKHTESHIM LTD. (IL) 2025-03-20 — — US disclosed
EP-4463438-A1 IMPROVED PROCESS OPTIMIZATION IN PRODUCTION OF AN INSECTICIDAL SUBSTANCE IN INDUSTRIAL SCALE ADAMA MAKHTESHIM LTD. (IL) 2024-11-20 — — EP disclosed
WO-2023135599-A1 IMPROVED PROCESS OPTIMIZATION IN PRODUCTION OF AN INSECTICIDAL SUBSTANCE IN INDUSTRIAL SCALE ADAMA MAKHTESHIM LTD. (IL) 2023-07-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091985-A1 IMPROVED PROCESS OPTIMIZATION IN PRODUCTION OF AN INSECTICIDAL SUBSTANCE IN INDUSTRIAL SCALE MAPT, TREH, ACHE MC4R 3738/4885FFAR1 2181/4885PDE2A 1292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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