Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | TIPARP | Q7Z3E1 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | IDE | P14735 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25309030 | 0.89 | TIPARP (0.63) | TNKSTIPARPPARP1KMT2A | |
| SCHEMBL25310056 | 0.88 | TNKS (0.49) | TNKSTIPARPPARP1CHRM1KMT2A | |
| SCHEMBL30510778 | 0.88 | TNKS (0.49) | TNKSTIPARPPARP1CHRM1KMT2A | |
| SCHEMBL30510770 | 0.87 | TNKS (0.51) | TNKSSMN1; SMN2ALDH1A1PARP1HTT | |
| SCHEMBL25309796 | 0.86 | TIPARP (0.67) | TIPARPPARP1KMT2A | |
| SCHEMBL25263299 | 0.86 | TNKS (0.53) | TNKSLMNATIPARPMAPTPARP1 | |
| SCHEMBL25309636 | 0.86 | TIPARP (0.59) | TNKSTIPARPPARP1KMT2A | |
| SCHEMBL25308758 | 0.85 | PARP1 (0.53) | TNKSSMN1; SMN2TIPARPALDH1A1MAPT | |
| SCHEMBL30510755 | 0.85 | PARP1 (0.53) | TNKSSMN1; SMN2TIPARPALDH1A1MAPT | |
| SCHEMBL25309613 | 0.85 | TNKS (0.47) | TNKSSMN1; SMN2TIPARPALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139536-A1 | (4-PIPERAZIN-1YL)-4-ALKYL-PHTHALAZIN-1(2H)-ONE COMPOUNDS AS PARP7 INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-07-27 | — | — | WO | claimed |
| WO-2023139536-A1 | (4-PIPERAZIN-1YL)-4-ALKYL-PHTHALAZIN-1(2H)-ONE COMPOUNDS AS PARP7 INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-07-27 | — | — | WO | disclosed |