Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382907 | 1.00 | VCAM1 (0.56) | VCAM1ALDH1A1HPGDHSD17B10TDP1 | |
| Selenium SCHEMBL9501261 | 0.98 | VCAM1 (0.55) | VCAM1ALDH1A1HPGDHSD17B10TDP1 | |
| Phenol SCHEMBL28138934 | 0.89 | VCAM1 (0.47) | VCAM1ALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL10337977 | 0.84 | ALDH1A1 (0.53) | VCAM1ALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL2235640 | 0.82 | VCAM1 (0.49) | VCAM1ALDH1A1HPGDPIN1MAPT | |
| SCHEMBL12286918 | 0.82 | HSD17B10 (0.52) | ALDH1A1HPGDHSD17B10TDP1MEN1 | |
| SCHEMBL30694393 | 0.82 | VCAM1 (0.47) | VCAM1ALDH1A1HPGDTDP1POLB | |
| SCHEMBL622040 | 0.82 | GPR35 (0.53) | VCAM1ALDH1A1HPGDTDP1CUL4A | |
| SCHEMBL220318 | 0.82 | VCAM1 (0.47) | VCAM1ALDH1A1HPGDTDP1POLB | |
| SCHEMBL27715362 | 0.81 | S100A4 (0.53) | VCAM1ALDH1A1HPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353715-B1 | 6-SUBSTITUTED CHIRALLY PURE DIFLUOROPIPERIDINE QUINAZOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR | WEISHANG SHANGHAI BIO PHARMACEUTICAL CO LTD (CN) | 2026-04-15 | — | — | EP | claimed |
| CN-120079375-A | Catalyst for synthesizing p-aminobenzonitrile and preparation method and application thereof | 濮阳市欧亚化工科技有限公司 | 2025-06-03 | — | — | CN | claimed |
| US-20250092015-A1 | A 6-substituted Chiral Pure Difluoropiperidine Quinazoline Derivative And Its Preparation Method | WEISHANG (SHANGHAI) BIO-PHARMACEUTICAL CO., LTD. (CN) | 2025-03-20 | — | — | US | claimed |
| CN-119143695-A | Preparation method and application of pyrene fluorescent probe for detecting copper ions and picric acid in series | 哈尔滨理工大学 | 2024-12-17 | — | — | CN | claimed |
| EP-4402478-A1 | METHOD FOR DETERMINING AT LEAST ONE ANALYTE OF INTEREST | F. Hoffmann-La Roche AG (CH) | 2024-07-24 | — | — | EP | claimed |
| US-20240219401-A1 | METHOD FOR DETERMINING AT LEAST ONE ANALYTE OF INTEREST | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2024-07-04 | — | — | US | claimed |
| CN-117957447-A | Method for determining at least one analyte of interest | 豪夫迈·罗氏有限公司 | 2024-04-30 | — | — | CN | claimed |
| EP-4353715-A1 | 6-SUBSTITUTED CHIRALLY PURE DIFLUOROPIPERIDINE QUINAZOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR | WEISHANG (SHANGHAI) BIO-PHARMACEUTICAL CO., LTD. (CN) | 2024-04-17 | — | — | EP | claimed |
| WO-2024016783-A1 | 6-SUBSTITUTED CHIRALLY PURE DIFLUOROPIPERIDINE QUINAZOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR | 威尚（上海）生物医药有限公司 | 2024-01-25 | — | — | WO | claimed |
| CN-115260153-B | 6-substituted chiral pure difluoropiperidine quinazoline derivative and preparation method thereof | 威尚（上海）生物医药有限公司 | 2023-10-27 | — | — | CN | claimed |
| EP-0097592-B1 | PROCESS FOR CATALYTICALLY REDUCING NITROAROMATIC COMPOUNDS | Montedison S.p.A. (IT) | 1986-12-10 | — | — | EP | claimed |
| EP-0159388-A2 | Preparation of nuclear chlorinated compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-10-30 | — | — | EP | claimed |
| US-4541962-A | Preparation of 4-(3-cyano-4-nitrophenyl)phenols | ETHYL CORPORATION (US) | 1985-09-17 | — | — | US | claimed |
| US-4535162-A | USING GROUP 8 METAL COORDINATION CATALYSTS | MONTEDISON S.P.A. (IT) | 1985-08-13 | — | — | US | claimed |
| US-4470930-A | Preparation of nuclear chlorinated aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-11 | — | — | US | claimed |
| EP-0097592-A2 | Process for catalytically reducing nitroaromatic compounds | Montedison S.p.A. (IT) | 1984-01-04 | — | — | EP | claimed |
| EP-0091383-A1 | Process for the catalytic reduction of nitro-aromatic compounds | Montedison S.p.A. (IT) | 1983-10-12 | — | — | EP | claimed |
| US-4343871-A | GROUP IA METAL ANODE AND CATHODE FORMED OF ORGANIC COMPOUND HAVINGPI-ELECTRON CONJUGATED SYSTEM | NIPPON TELEGRAPH & TELEPHONE PUBLIC CORPORATION (JP) | 1982-08-10 | — | — | US | claimed |
| US-4151165-A | USING AN AROMATIC NITRO COMPOUND IN OXYGEN-FREE, AQUEOUS ENVIRONMENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-04-24 | — | — | US | claimed |
| US-3979431-A | Process for preparing nitroaromatic nitriles | CHEVRON RESEARCH COMPANY (US) | 1976-09-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092015-A1 | A 6-substituted Chiral Pure Difluoropiperidine Quinazoline Derivative And Its Preparation Method | CYP2D6, QDPR, FDPS | VCAM1 4579/4885ALDH1A1 1199/4885HPGD 1482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.