Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
| ▸ | EPOR | P19235 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070956 | 1.00 | KMT2A (0.57) | KMT2ASMN1; SMN2MAOBALOX5LTA4H | |
| SCHEMBL3485036 | 0.88 | KMT2A (0.56) | KMT2ASMN1; SMN2MAOBALOX5NR4A2 | |
| SCHEMBL2927329 | 0.87 | KMT2A (0.55) | KMT2ASMN1; SMN2MAOBALOX5LTA4H | |
| SCHEMBL9019941 | 0.85 | KMT2A (0.59) | KMT2ASMN1; SMN2MAOBALOX5LTA4H | |
| SCHEMBL9432429 | 0.85 | KMT2A (0.59) | KMT2ASMN1; SMN2MAOBALOX5LTA4H | |
| SCHEMBL2853880 | 0.85 | ALOX5 (0.63) | KMT2ASMN1; SMN2MAOBALOX5LTA4H | |
| SCHEMBL3251101 | 0.85 | LTA4H (0.57) | SMN1; SMN2MAOBALOX5LTA4HNR4A2 | |
| SCHEMBL3609023 | 0.84 | KMT2A (0.64) | KMT2ASMN1; SMN2MAOBALOX5LTA4H | |
| SCHEMBL16767403 | 0.81 | PPARG (0.66) | KMT2ASMN1; SMN2MAOBALOX5LTA4H | |
| SCHEMBL30771265 | 0.81 | SGMS2 (0.58) | KMT2ASMN1; SMN2MAOBALOX5LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137634-A1 | TRICYCLIC COMPOUND, PREPARATION THEREFOR, PHARMACEUTICAL COMPOSITION AND USE | 上海奕拓医药科技有限责任公司 | 2023-07-27 | — | — | WO | disclosed |
| WO-2023137634-A1 | TRICYCLIC COMPOUND, PREPARATION THEREFOR, PHARMACEUTICAL COMPOSITION AND USE | 上海奕拓医药科技有限责任公司 | 2023-07-27 | — | — | WO | disclosed |