Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | EPOR | P19235 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27833465 | 0.87 | ALOX5 (0.67) | ALOX5KMT2ASMN1; SMN2PTGS1MAOB | |
| SCHEMBL2986567 | 0.87 | ALOX5 (0.67) | ALOX5KMT2ASMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL9432429 | 0.86 | KMT2A (0.59) | ALOX5KMT2ASMN1; SMN2LTA4HMAOB | |
| SCHEMBL9019941 | 0.86 | KMT2A (0.59) | ALOX5KMT2ASMN1; SMN2LTA4HMAOB | |
| SCHEMBL25311665 | 0.85 | KMT2A (0.57) | ALOX5KMT2ASMN1; SMN2LTA4HMAOB | |
| SCHEMBL31070956 | 0.85 | KMT2A (0.57) | ALOX5KMT2ASMN1; SMN2LTA4HMAOB | |
| SCHEMBL3609023 | 0.85 | KMT2A (0.64) | ALOX5KMT2ASMN1; SMN2LTA4HMAOB | |
| SCHEMBL6266373 | 0.85 | LTA4H (0.59) | ALOX5SMN1; SMN2LTA4HMAOBACACB | |
| SCHEMBL23718140 | 0.82 | CASR (0.53) | ALOX5KMT2ASMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL16767403 | 0.82 | PPARG (0.66) | ALOX5KMT2ASMN1; SMN2LTA4HMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |