Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989714 | 1.00 | CYP11B1 (0.31) | CYP11B1CYP11B2NOTUM | |
| SCHEMBL30989785 | 0.73 | NOTUM (0.31) | NOTUM | |
| SCHEMBL11268817 | 0.71 | ALDH1A1 (0.45) | CYP11B1CYP11B2 | |
| SCHEMBL30488533 | 0.71 | ALDH1A1 (0.45) | CYP11B1CYP11B2 | |
| SCHEMBL29257102 | 0.71 | PIK3CD (0.33) | — | |
| SCHEMBL30446971 | 0.71 | PIK3CD (0.33) | — | |
| SCHEMBL30488561 | 0.68 | TLR8 (0.43) | CYP11B2 | |
| SCHEMBL25258684 | 0.68 | TLR8 (0.43) | CYP11B2 | |
| SCHEMBL18508459 | 0.67 | L3MBTL1 (0.37) | CYP11B1CYP11B2 | |
| SCHEMBL30989709 | 0.65 | NOTUM (0.38) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | CYCS, CYP2E1, AHR | CYP11B1 132/4885CYP11B2 106/4885NOTUM 2199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.