SCHEMBL25314031

SCHEMBL25314031

COC(=O)c1ccc(Oc2cc(C#N)cc(Oc3ccc(C(=O)OC)cc3)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
MAPT P10636 6/20 0.53
PARP15 Q460N3 1/20 0.53
PARP10 Q53GL7 1/20 0.53
PARP2 Q9UGN5 1/20 0.53
RAB9A P51151 4/20 0.47
LMNA P02545 3/20 0.47
POLB P06746 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
PKM P14618 1/20 0.47
MAPK1 P28482 1/20 0.47
IL18 Q14116 1/20 0.47
USP2 O75604 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8229744 0.90 PARP15 (0.65) CA1CA2MAPTPARP15PARP10
SCHEMBL25314649 0.87 PARP15 (0.57) CA1CA2MAPTPARP15PARP10
SCHEMBL28676041 0.87 USP2 (0.49) CA1CA2MAPTPARP15PARP10
SCHEMBL69218 0.82 CA1 (0.75) CA1CA2MAPTPARP15PARP10
SCHEMBL2086052 0.82 CA12 (0.53) CA1CA2MAPTPARP15PARP10
SCHEMBL4258396 0.81 CA1 (0.50) CA1CA2MAPTPARP15PARP10
SCHEMBL7393 0.81 CA1 (0.57) CA1CA2MAPTPOLBTDP1
SCHEMBL3602828 0.81 PARP15 (0.47) MAPTPARP15PARP10PARP2RAB9A
SCHEMBL25317291 0.80 CYP11B1 (0.47) RAB9APOLBUSP2SMN1; SMN2NPC1
SCHEMBL13268611 0.80 CYP11B1 (0.59) MAPTPARP15PARP10PARP2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof SICHUAN UNIVERSITY (CN) 2026-02-24 US disclosed
US-20230235116-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT ANTI-DRIPPING COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SICHUAN UNIVERSITY (CN) 2023-07-27 US disclosed
EP-4169967-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT DROPLET-RESISTANT COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Sichuan University (CN) 2023-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof COL1A1, F11, COL2A1 CA1 1744/4885CA2 1930/4885MAPT 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.