SCHEMBL25317291

SCHEMBL25317291

COC(=O)c1cc(Oc2cccc(C#N)c2)cc(C(=O)OC)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.47
CYP11B2 P19099 2/20 0.47
USP2 O75604 1/20 0.47
P4HB P07237 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PRSS1 P07477 1/20 0.45
ACR P10323 1/20 0.45
PLAU P00749 1/20 0.45
MRGPRX4 Q96LA9 1/20 0.44
GRM5 P41594 2/20 0.44
TDP2 O95551 1/20 0.44
BTK Q06187 2/20 0.43
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
RAB9A P51151 1/20 0.43
BLM P54132 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28676041 0.86 USP2 (0.49) CYP11B1CYP11B2USP2L3MBTL1PLAU
SCHEMBL25314649 0.83 PARP15 (0.57) CYP11B1CYP11B2USP2PLAUPOLB
SCHEMBL13268611 0.82 CYP11B1 (0.59) CYP11B1CYP11B2L3MBTL1PLAUMRGPRX4
SCHEMBL8513184 0.82 F10 (0.50) L3MBTL1PRSS1ACRGRM5
SCHEMBL60040 0.81 MRGPRX4 (0.56) CYP11B1CYP11B2P4HBPLAUMRGPRX4
SCHEMBL30444713 0.81 MRGPRX4 (0.56) CYP11B1CYP11B2P4HBPLAUMRGPRX4
SCHEMBL890626 0.80 USP2 (0.66) CYP11B1CYP11B2USP2L3MBTL1PRSS1
SCHEMBL25314031 0.80 CA1 (0.53) CYP11B1CYP11B2USP2PRSS1NPC1
SCHEMBL21711982 0.80 MAPT (0.51) USP2L3MBTL1SMN1; SMN2
SCHEMBL8511723 0.80 AKR1C3 (0.57) PRSS1ACRGRM5PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof SICHUAN UNIVERSITY (CN) 2026-02-24 US disclosed
US-20230235116-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT ANTI-DRIPPING COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SICHUAN UNIVERSITY (CN) 2023-07-27 US disclosed
EP-4169967-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT DROPLET-RESISTANT COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Sichuan University (CN) 2023-04-26 EP disclosed
CN-113817152-B Flame-retardant anti-dripping copolyester based on high-temperature self-crosslinking and preparation method and application thereof 四川大学 2022-11-11 CN disclosed
CN-113817152-A Flame-retardant anti-dripping copolyester based on high-temperature self-crosslinking and preparation method and application thereof 四川大学 2021-12-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof COL1A1, F11, COL2A1 CYP11B1 120/4885CYP11B2 249/4885USP2 2337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.