Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601091 | 0.83 | HPGD (0.50) | MEN1KMT2AOPRM1OPRK1OPRL1 | |
| SCHEMBL3923485 | 0.83 | HPGD (0.50) | MEN1KMT2AOPRM1OPRK1OPRL1 | |
| SCHEMBL12049027 | 0.81 | MEN1 (0.50) | POLBSMN1; SMN2MEN1KMT2ASRD5A1 | |
| SCHEMBL5606110 | 0.73 | CA12 (0.40) | TSHRSMN1; SMN2MEN1KMT2AHSD17B3 | |
| SCHEMBL7086526 | 0.72 | PARL (0.30) | — | |
| SCHEMBL6333644 | 0.71 | MAOA (0.40) | HSD17B3 | |
| SCHEMBL1396793 | 0.71 | POLB (0.51) | POLBSMN1; SMN2MEN1KMT2ASRD5A1 | |
| SCHEMBL3389475 | 0.71 | POLB (0.51) | POLBSMN1; SMN2MEN1KMT2ASRD5A1 | |
| SCHEMBL11404877 | 0.71 | POLB (0.56) | POLBSMN1; SMN2MEN1KMT2ASRD5A1 | |
| SCHEMBL2142614 | 0.71 | POLB (0.56) | POLBSMN1; SMN2MEN1KMT2ASRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897370-A | Heterocyclic compounds and their use | 凯悦施那有限公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |