Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17655666 | 0.88 | ACHE (0.48) | ACHEPTGS1PTGS2HSD17B10KDM4E | |
| SCHEMBL8542113 | 0.79 | KDM4E (0.55) | PTGS1PTGS2HSD17B10KDM4EMAPT | |
| SCHEMBL14363097 | 0.79 | ACHE (0.59) | ACHEHSD17B10KDM4ENPSR1MAPT | |
| SCHEMBL20970915 | 0.78 | HTR2A (0.66) | PTGS1PTGS2HSD17B10KDM4ELMNA | |
| SCHEMBL9709192 | 0.77 | HSD17B10 (0.50) | PTGS1PTGS2HSD17B10LMNANPSR1 | |
| SCHEMBL7457596 | 0.77 | HSD17B10 (0.54) | PTGS1PTGS2HSD17B10KDM4EMAPT | |
| SCHEMBL9709129 | 0.77 | HSD17B10 (0.50) | PTGS1PTGS2HSD17B10LMNANPSR1 | |
| SCHEMBL8547102 | 0.77 | KDM4E (0.52) | PTGS1PTGS2HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL17655655 | 0.77 | PTGS1 (0.40) | ACHEPTGS1PTGS2HSD17B10KDM4E | |
| SCHEMBL22215821 | 0.76 | SMN1; SMN2 (0.55) | HSD17B10KDM4ELMNAMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059153-A1 | BICYCLIC QUINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | IC-MedTech Corp. | 2025-02-20 | — | — | US | disclosed |
| EP-4465981-A1 | BICYCLIC QUINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | IC-Medtech Corp. (US) | 2024-11-27 | — | — | EP | disclosed |
| CN-118891036-A | Bicyclic quinones, pharmaceutical compositions and therapeutic uses | IC医药科技公司 | 2024-11-01 | — | — | CN | disclosed |
| WO-2023141410-A1 | BICYCLIC QUINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | IC-MedTech Corp. (US) | 2023-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059153-A1 | BICYCLIC QUINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | SDHA, NQO1, NDUFA7 | ACHE 328/4885PTGS1 344/4885PTGS2 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.