Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709192 | 0.86 | HSD17B10 (0.50) | HSD17B10LMNANPSR1MAPTALDH1A1 | |
| SCHEMBL4879810 | 0.80 | ALDH1A1 (0.56) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL20970915 | 0.80 | HTR2A (0.66) | HSD17B10LMNANPSR1MAPTALDH1A1 | |
| SCHEMBL5307529 | 0.78 | HSD17B10 (0.43) | HSD17B10LMNANPSR1MAPTALDH1A1 | |
| SCHEMBL5307526 | 0.78 | HSD17B10 (0.43) | HSD17B10LMNANPSR1MAPTALDH1A1 | |
| SCHEMBL25317242 | 0.77 | ACHE (0.50) | HSD17B10LMNANPSR1MAPTALDH1A1 | |
| SCHEMBL1706883 | 0.77 | PTGS2 (0.64) | MAPTPTGS2HTR2AHTR2CHTR2B | |
| SCHEMBL15432994 | 0.76 | MAOB (0.40) | HSD17B10LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7457596 | 0.76 | HSD17B10 (0.54) | HSD17B10MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9709272 | 0.75 | ALDH1A1 (0.53) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471516-A1 | Tricyclic heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-19 | — | — | EP | disclosed |