SCHEMBL2531803

SCHEMBL2531803

CC(=O)N(C)c1cccc(C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 10/20 0.57
HSD17B2 P37059 10/20 0.57
SIGMAR1 Q99720 1/20 0.51
LMNA P02545 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TSHR P16473 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ALDH1A1 P00352 1/20 0.46
RAB9A P51151 1/20 0.46
BRD4 O60885 1/20 0.46
LIN28A Q9H9Z2 1/20 0.46
NR1I2 O75469 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C9 P11712 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTR2B P41595 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29674755 1.00 HSD17B1 (0.57) HSD17B1HSD17B2SIGMAR1LMNASMN1; SMN2
SCHEMBL30229852 0.84 HSD17B1 (0.57) HSD17B1HSD17B2SIGMAR1LMNASMN1; SMN2
SCHEMBL1684295 0.84 HSD17B1 (0.57) HSD17B1HSD17B2SIGMAR1LMNASMN1; SMN2
SCHEMBL6632095 0.84 HSD17B1 (0.57) HSD17B1HSD17B2SIGMAR1LMNASMN1; SMN2
SCHEMBL2088201 0.84 HSD17B1 (0.57) HSD17B1HSD17B2SIGMAR1LMNASMN1; SMN2
SCHEMBL30937218 0.82 HSD17B1 (0.55) HSD17B1HSD17B2SIGMAR1LMNASMN1; SMN2
Ammonia Solution, Strong SCHEMBL28786422 0.82 HSD17B1 (0.55) HSD17B1HSD17B2SIGMAR1LMNASMN1; SMN2
SCHEMBL10945242 0.82 HSD17B1 (0.55) HSD17B1HSD17B2SIGMAR1LMNASMN1; SMN2
SCHEMBL19512929 0.82 HSD17B1 (0.55) HSD17B1HSD17B2SIGMAR1LMNASMN1; SMN2
SCHEMBL29460303 0.82 HSD17B1 (0.55) HSD17B1HSD17B2SIGMAR1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3858943-B1 SURFACE TREATMENT AGENT DAIKIN IND LTD (JP) 2024-02-28 EP disclosed
US-11814537-B2 Silane compound containing perfluoro (poly ) ether group DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-11814537-B2 Silane compound containing perfluoro (poly ) ether group DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
WO-2023210400-A1 HEAT-CURABLE PERFLUOROPOLYETHER RUBBER COMPOSITION 信越化学工業株式会社 2023-11-02 WO disclosed
US-11760062-B2 Article having surface treatment layer DAIKIN INDUSTRIES, LTD. (JP) 2023-09-19 US disclosed
US-11760062-B2 Article having surface treatment layer DAIKIN INDUSTRIES, LTD. (JP) 2023-09-19 US disclosed
US-20230273348-A1 SURFACE TREATMENT COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2023-08-31 US disclosed
US-20230273348-A1 SURFACE TREATMENT COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2023-08-31 US disclosed
US-20230257528-A1 SURFACE TREATING COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2023-08-17 US disclosed
US-20230257528-A1 SURFACE TREATING COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2023-08-17 US disclosed
US-20090099233-A1 HETEROARYL AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS VERTEX PHARMACEUTICALS INCORPORATED 2009-04-16 US disclosed
US-20080114120-A1 Coating composition SHIN-ETSU CHEMICAL CO. LTD. 2008-05-15 US disclosed
US-20080114120-A1 Coating composition SHIN-ETSU CHEMICAL CO. LTD. 2008-05-15 US disclosed
US-20070270471-A1 Compounds Which Potentiate Glutamate Receptor and Uses Thereof in Medicine GLAXO GROUP LIMITED (GB) 2007-11-22 US disclosed
US-20060178375-A1 Heteroaryloxy nitrogenous saturated heterocyclic derivative MSD K.K. (JP) 2006-08-10 US disclosed
EP-1642898-A1 HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-04-05 EP disclosed
EP-1317459-B1 BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS ASTRAZENECA AB (SE) 2004-04-07 EP disclosed
US-20030232875-A1 Bicyclic pyrrolyl amides as glucogen phosphorylase inhibitors ASTRAZENECA AB (SE) 2003-12-18 US disclosed
EP-1317459-A1 BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS AstraZeneca AB (SE) 2003-06-11 EP disclosed
WO-2002020530-A1 BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS ASTRAZENECA AB (SE) 2002-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090099233-A1 HETEROARYL AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS CACNA1B, SCN3A, SCN2A HSD17B1 3952/4885HSD17B2 3809/4885SIGMAR1 1088/4885
US-20030232875-A1 Bicyclic pyrrolyl amides as glucogen phosphorylase inhibitors GYS1, GYS2, PYGL HSD17B1 928/4885HSD17B2 1146/4885SIGMAR1 1258/4885
US-20060178375-A1 Heteroaryloxy nitrogenous saturated heterocyclic derivative HRH3, HRH4, HCRTR2 HSD17B1 389/4885HSD17B2 279/4885SIGMAR1 63/4885
US-20070270471-A1 Compounds Which Potentiate Glutamate Receptor and Uses Thereof in Medicine GRM3, GLRA3, GLRA1 HSD17B1 1086/4885HSD17B2 993/4885SIGMAR1 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.