Tert-Butanol

Tert-Butanol

SCHEMBL25318413

CC(C)(C)O.CC(C)(C)O.O=C(O)OC(=O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
ALDH1A1 P00352 2/20 0.47
HMGCR P04035 1/20 0.38
CHRM1 P11229 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
FFAR3 O14843 2/20 0.33
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL27603251 0.81
SCHEMBL7793 0.80
SCHEMBL31313730 0.80 CA1 (0.40) TSHRALDH1A1FFAR3LCKFYN
SCHEMBL28967242 0.77 FFAR3 (0.38) TSHRALDH1A1FFAR3LCKFYN
Acetic Acid SCHEMBL4217515 0.77 FFAR3 (0.58) TSHRALDH1A1FFAR3LCKFYN
Acetone SCHEMBL11030092 0.77 LMNA (0.50) TSHRALDH1A1FFAR3LCKFYN
Tert-Butanol SCHEMBL6194876 0.76 ALDH1A1 (0.61) TSHRALDH1A1HMGCRCHRM1TBXA2R
Tert-Butanol SCHEMBL8169028 0.76
Tert-Butanol SCHEMBL1204871 0.76 ALDH1A1 (0.61) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL4842000 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116675814-A Mud-resistant slow-release slump retaining agent and preparation method thereof 杭州构建新型材料有限公司 2023-09-01 CN claimed
CN-117771378-A Pharmaceutical composition for improving bioavailability of KRAS inhibitor and application thereof 贝达药业股份有限公司 2024-03-29 CN disclosed
CN-116675814-A Mud-resistant slow-release slump retaining agent and preparation method thereof 杭州构建新型材料有限公司 2023-09-01 CN disclosed
WO-2023138524-A1 KRAS G12D DEGRADATION AGENT AND MEDICAL USE THEREOF 贝达药业股份有限公司 2023-07-27 WO disclosed
WO-2023072188-A1 KRAS G12D INHIBITORS AND USE THEREOF IN MEDICINE 贝达药业股份有限公司 2023-05-04 WO disclosed