Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527517 | 0.90 | LMNA (0.44) | ADRB3 | |
| SCHEMBL2525773 | 0.90 | GPR119 (0.42) | ADRB3PPARGPPARAFFAR1MAOB | |
| SCHEMBL2528740 | 0.90 | CYP1A2 (0.38) | ADRB3PPARGPPARAMAPTGAA | |
| SCHEMBL2527514 | 0.90 | PDGFRB (0.41) | ADRB3GAAKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL2529623 | 0.89 | ADRB3 (0.45) | ADRB3PPARGPPARAGAAKDM4E | |
| SCHEMBL2528949 | 0.89 | L3MBTL1 (0.42) | ADRB3PPARGPPARAMAPTL3MBTL1 | |
| SCHEMBL2526470 | 0.88 | MEN1 (0.42) | MAPTMAOB | |
| SCHEMBL2526478 | 0.88 | PPARG (0.38) | ADRB3PPARGPPARAL3MBTL1GAA | |
| SCHEMBL2533454 | 0.88 | VNN1 (0.43) | ADRB3 | |
| SCHEMBL2530860 | 0.87 | FFAR1 (0.39) | ADRB3MAPTL3MBTL1SMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | ADRB3 557/4885PPARG 1096/4885PPARA 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.