Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634212 | 0.82 | LMNA (0.42) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3634956 | 0.78 | TRPV1 (0.43) | MEN1KMT2ALMNABACE1GSK3B | |
| SCHEMBL27389237 | 0.76 | MEN1 (0.45) | MAPTMEN1KMT2ALMNAPSMD14 | |
| SCHEMBL30881071 | 0.76 | MEN1 (0.45) | MAPTMEN1KMT2ALMNAPSMD14 | |
| SCHEMBL3633702 | 0.75 | DHODH (0.51) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL4532966 | 0.71 | TKT (0.33) | — | |
| SCHEMBL3634805 | 0.71 | L3MBTL1 (0.47) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL13730057 | 0.70 | BCL6 (0.51) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL479544 | 0.70 | DHODH (0.57) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL25319703 | 0.70 | CRHBP (0.45) | MAPTMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466258-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |