Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | BLVRB | P30043 | 1/20 | 0.38 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4152592 | 0.91 | ALDH1A1 (0.52) | ALDH1A1HPGDNPSR1TNK2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4163294 | 0.90 | ALDH1A1 (0.51) | ALDH1A1HPGDNPSR1TNK2SMN1; SMN2 | |
| SCHEMBL4159263 | 0.90 | SLC22A12 (0.41) | ALDH1A1HPGDNPSR1SCN9AXDH | |
| SCHEMBL4141873 | 0.90 | ALDH1A1 (0.38) | ALDH1A1HPGDNPSR1SCN9ASMN1; SMN2 | |
| SCHEMBL2535698 | 0.90 | SLC22A12 (0.44) | ALDH1A1HPGDNPSR1SCN9AKDM4E | |
| SCHEMBL4146990 | 0.89 | SLC22A12 (0.46) | ALDH1A1HPGDNPSR1SCN9ASMN1; SMN2 | |
| SCHEMBL4154840 | 0.89 | SLC22A12 (0.44) | ALDH1A1HPGDNPSR1SCN9ASMN1; SMN2 | |
| Potassium SCHEMBL4146433 | 0.89 | ALDH1A1 (0.37) | ALDH1A1HPGDNPSR1SCN9ASMN1; SMN2 | |
| SCHEMBL4146427 | 0.89 | ALDH1A1 (0.37) | ALDH1A1HPGDNPSR1SCN9ASMN1; SMN2 | |
| SCHEMBL4300552 | 0.87 | ALDH1A1 (0.36) | ALDH1A1HPGDNPSR1SCN9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3263109-B1 | DRUG FOR PREVENTING AND/OR TREATING DEMENTIA | NAT UNIV CORP TOTTORI UNIV (JP) | 2020-06-17 | — | — | EP | claimed |
| EP-3219319-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | Nippon Chemiphar Co., Ltd. (JP) | 2017-09-20 | — | — | EP | claimed |
| EP-2036561-B1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | NIPPON CHEMIPHAR CO (JP) | 2017-05-10 | — | — | EP | claimed |
| US-20110257201-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 2011-10-20 | — | — | US | claimed |
| US-20100234399-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 2010-09-16 | — | — | US | claimed |
| EP-2036561-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | Nippon Chemiphar Co., Ltd. (JP) | 2009-03-18 | — | — | EP | claimed |
| EP-3263109-B1 | DRUG FOR PREVENTING AND/OR TREATING DEMENTIA | NAT UNIV CORP TOTTORI UNIV (JP) | 2020-06-17 | — | — | EP | disclosed |
| US-10413546-B2 | Drug for preventing and/or treating dementia | NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) | 2019-09-17 | — | — | US | disclosed |
| US-20180117047-A1 | DRUG FOR PREVENTING AND/OR TREATING DEMENTIA | NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) | 2018-05-03 | — | — | US | disclosed |
| EP-3263109-A1 | DRUG FOR PREVENTING AND/OR TREATING DEMENTIA | National University Corporation Tottori University (JP) | 2018-01-03 | — | — | EP | disclosed |
| EP-3219319-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | Nippon Chemiphar Co., Ltd. (JP) | 2017-09-20 | — | — | EP | disclosed |
| EP-3219319-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | Nippon Chemiphar Co., Ltd. (JP) | 2017-09-20 | — | — | EP | disclosed |
| EP-2036561-B1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | NIPPON CHEMIPHAR CO (JP) | 2017-05-10 | — | — | EP | disclosed |
| US-20100234399-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| CN-101505755-A | Agent for overcoming resistance to anticancer drug | NIPPON CHEMIPHAR CO (JP) | 2009-08-12 | — | — | CN | disclosed |
| US-20090149452-A1 | XANTHINE OXIDASE INHIBITOR | NIPPON CHEMIPHAR CO., LTD. (JP) | 2009-06-11 | — | — | US | disclosed |
| EP-2036561-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | Nippon Chemiphar Co., Ltd. (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-2036561-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | Nippon Chemiphar Co., Ltd. (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1911760-A1 | XANTHINE OXIDASE INHIBITOR | Nippon Chemiphar Co., Ltd. (JP) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007148835-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180117047-A1 | DRUG FOR PREVENTING AND/OR TREATING DEMENTIA | XDH, ACHE, DDO | ALDH1A1 455/4885HPGD 34/4885NPSR1 1390/4885 |
| US-20090149452-A1 | XANTHINE OXIDASE INHIBITOR | XDH, PNPO, CBR1 | ALDH1A1 304/4885HPGD 143/4885NPSR1 751/4885 |
| US-10413546-B2 | Drug for preventing and/or treating dementia | XDH, ACHE, DDO | ALDH1A1 455/4885HPGD 34/4885NPSR1 1390/4885 |
| US-20100234399-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | TMX1, TPX2, XDH | ALDH1A1 1351/4885HPGD 386/4885NPSR1 4617/4885 |
| US-20110257201-A1 | AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT | TMX1, TPX2, XDH | ALDH1A1 1351/4885HPGD 386/4885NPSR1 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.