SCHEMBL25322115

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6543659	0.98	CHRM2 (0.51)	CHRM2ADRA2BDRD3SIGMAR1HRH3
	SCHEMBL11668730	0.84	ALDH1A1 (0.62)	ALDH1A1LMNACYP3A4CYP2C19GAA
	SCHEMBL16267250	0.84	PADI1 (0.47)	CHRM2ADRA2BDRD3SIGMAR1HRH3
	SCHEMBL64561	0.82	CHRM2 (0.46)	CHRM2ADRA2BDRD3SIGMAR1HRH3
	SCHEMBL16267349	0.82	CYP3A4 (0.38)	CHRM2ADRA2BDRD3SIGMAR1HRH3
	SCHEMBL1863187	0.81	CYP3A4 (0.43)	CHRM2ADRA2BDRD3SIGMAR1HRH3
	SCHEMBL16265608	0.81	CYP3A4 (0.43)	CHRM2ADRA2BDRD3SIGMAR1HRH3
	SCHEMBL9774559	0.81	CHRM2 (0.49)	CHRM2ADRA2BDRD3SIGMAR1HRH3
	SCHEMBL2959602	0.81	KMT2A (0.43)	CHRM2ADRA2BDRD3SIGMAR1HRH3
	SCHEMBL1857702	0.80	CYP3A4 (0.42)	CHRM2ADRA2BDRD3SIGMAR1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.