Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30675555 | 0.83 | ADORA3 (0.51) | ALDH1A1TSHRKDM4EADORA3MEN1 | |
| SCHEMBL9753194 | 0.78 | SORT1 (0.53) | ALDH1A1KDM4EL3MBTL1ADORA3NPC1 | |
| SCHEMBL15556909 | 0.76 | MAPK8 (0.48) | ALDH1A1TSHRKDM4EADORA3ADORA2A | |
| SCHEMBL28545686 | 0.75 | PTK2 (0.51) | KDM4EL3MBTL1ADORA3MAPTNPC1 | |
| SCHEMBL7092192 | 0.75 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EL3MBTL1ADORA3MAPT | |
| SCHEMBL9974219 | 0.75 | KDM4E (0.46) | ALDH1A1KDM4EL3MBTL1ADORA3NPC1 | |
| SCHEMBL19736135 | 0.75 | GRM5 (0.50) | KDM4EL3MBTL1ADORA3ADORA2AADORA2B | |
| SCHEMBL1269767 | 0.75 | RAB9A (0.60) | ALDH1A1KDM4EL3MBTL1MAPTNPC1 | |
| SCHEMBL2019170 | 0.75 | KDM4E (0.46) | ALDH1A1KDM4EL3MBTL1ADORA3NPC1 | |
| SCHEMBL12513100 | 0.74 | MAPK8 (0.47) | ALDH1A1KDM4EL3MBTL1ADORA3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017979-A1 | PROCESS FOR THE PREPARATION OF 2-N-ACYLAMINOPYRIDINES AND 2-AMINOPYRIDINES FROM 5-OXOALKANENITRILE OXIMES | DSM N.V. (NL) | 1991-11-28 | — | — | WO | disclosed |