Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 7/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30551254 | 1.00 | CYP1A2 (0.38) | CYP1A2GRM5ALDH1A1BTKRIPK2 | |
| SCHEMBL25322394 | 0.95 | ALDH1A1 (0.41) | CYP1A2GRM5ALDH1A1BTKRIPK2 | |
| SCHEMBL25321038 | 0.76 | PARP1 (0.36) | CYP1A2GRM5 | |
| SCHEMBL25322726 | 0.75 | PARP1 (0.35) | CYP1A2GRM5 | |
| SCHEMBL30551412 | 0.73 | PRF1 (0.31) | — | |
| SCHEMBL25319613 | 0.73 | PRF1 (0.31) | — | |
| SCHEMBL10009086 | 0.72 | MAOA (0.49) | CYP1A2GRM5 | |
| SCHEMBL24879177 | 0.68 | WNT3A (0.53) | ALDH1A1ROCK2 | |
| SCHEMBL17133429 | 0.67 | NTRK1 (0.49) | CYP1A2GRM5RIPK2RIPK1RIPK3 | |
| SCHEMBL24367126 | 0.67 | ALDH1A1 (0.55) | ALDH1A1BTKMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |