Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530961 | 0.98 | ACHE (0.47) | ACHECYP4F2CYP4A11NAAAALDH1A1 | |
| SCHEMBL2531108 | 0.98 | ACHE (0.47) | ACHECYP4F2CYP4A11NAAAALDH1A1 | |
| SCHEMBL2529912 | 0.93 | ACHE (0.37) | ACHECYP4F2CYP4A11NAAAALDH1A1 | |
| SCHEMBL8421539 | 0.87 | NAAA (0.44) | ACHENAAAALDH1A1CYP3A4TSHR | |
| SCHEMBL27982814 | 0.87 | NAAA (0.44) | ACHENAAAALDH1A1CYP3A4TSHR | |
| SCHEMBL2550989 | 0.85 | TSHR (0.56) | ACHECYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL9480850 | 0.85 | ALDH1A1 (0.40) | NAAAALDH1A1CYP3A4TSHREPHX1 | |
| SCHEMBL6060295 | 0.84 | ACHE (0.43) | ACHECYP4F2CYP4A11NAAAALDH1A1 | |
| Ethylene Glycol Diisobutanoate SCHEMBL2948671 | 0.82 | CHRNB2 (0.34) | ACHECYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL863285 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| CN-107532302-B | Photonasty electroless plating substrate agent | 日产化学工业株式会社 | 2019-10-08 | — | — | CN | disclosed |
| CN-107532302-A | Photonasty electroless plating substrate agent | 日产化学工业株式会社 | 2018-01-02 | — | — | CN | disclosed |
| CN-102186865-A | Method for producing dialkylphosphinic acids, esters and salts using acrylonitrile, and use thereof | CLARIANT INT LTD | 2011-09-14 | — | — | CN | disclosed |
| CN-102186864-A | Method for producing dialkylphosphinic acids, esters and salts using acrylic acid derivatives, and use thereof | CLARIANT INT LTD | 2011-09-14 | — | — | CN | disclosed |
| CN-102177164-A | Method for producing dialkylphosphinic acids and esters and salts thereof by means of allyl alcohols/acroleins and use thereof | CLARIANT FINANCE BVI LTD | 2011-09-07 | — | — | CN | disclosed |
| US-20100247597-A1 | Biocompatible Polymers for Coating or Fabricating Implantable Medical Devices | Medtroni Vascular, Inc. (US) | 2010-09-30 | — | — | US | disclosed |
| US-5985869-A | USEFUL AS VASODILATORS, HYPOTENSIVE AGENTS, WATER DIURETICS, PLATELET AGGLUTINATION INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| EP-0450097-B1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247597-A1 | Biocompatible Polymers for Coating or Fabricating Implantable Medical Devices | CD47, CD209, TLR3 | ACHE 3072/4885CYP4F2 2486/4885CYP4A11 4612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.