Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584018 | 0.87 | PLA2G2A (0.61) | HTR6PLA2G2ALMNAALDH1A1MTNR1A | |
| SCHEMBL27649356 | 0.86 | LTB4R (0.50) | HTR6PLA2G2ALMNAALDH1A1KMT2A | |
| SCHEMBL16494825 | 0.81 | HTR6 (0.64) | HTR6PLA2G2ALMNAALDH1A1MTNR1A | |
| SCHEMBL25322499 | 0.81 | PTGS2 (0.54) | HTR6LMNAALDH1A1KMT2A | |
| SCHEMBL10624757 | 0.80 | LTB4R (0.60) | HTR6PLA2G2ALMNAALDH1A1MTNR1A | |
| SCHEMBL28524187 | 0.80 | LTB4R (0.57) | HTR6PLA2G2ALMNAALDH1A1PPARG | |
| SCHEMBL10624765 | 0.80 | LTB4R (0.60) | HTR6PLA2G2ALMNAALDH1A1MTNR1A | |
| SCHEMBL29092647 | 0.80 | HTR6 (0.66) | HTR6PLA2G2ALMNAALDH1A1MTNR1A | |
| SCHEMBL9583699 | 0.79 | HTR6 (0.72) | HTR6PLA2G2ALMNAALDH1A1MTNR1A | |
| SCHEMBL12083183 | 0.79 | PLA2G2A (0.74) | HTR6PLA2G2ALMNAALDH1A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137771-A1 | METHOD FOR SYNTHESIZING α-ALKYL SUBSTITUTED INDOLE-3-CARBOXALDEHYDE COMPOUND | 苏州大学 | 2023-07-27 | — | — | WO | disclosed |
| CN-114478351-B | Method for synthesizing alpha-alkyl substituted indole-3-formaldehyde compound | 苏州大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-114478351-A | Method for synthesizing alpha-alkyl substituted indole-3-formaldehyde compound | 苏州大学 | 2022-05-13 | — | — | CN | disclosed |