Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25327914 | 0.87 | KIF11 (0.44) | RIPK1KIF11 | |
| SCHEMBL25327034 | 0.86 | SLC6A9 (0.39) | RIPK1PDE5AKIF11SLC6A9 | |
| SCHEMBL30522928 | 0.85 | RIPK1 (0.40) | RIPK1PDE5ATP53MDM2MAOA | |
| SCHEMBL30522979 | 0.85 | RIPK1 (0.40) | RIPK1PDE5ATP53MDM2MAOA | |
| SCHEMBL25324773 | 0.85 | RIPK1 (0.40) | RIPK1PDE5ATP53MDM2MAOA | |
| SCHEMBL25324778 | 0.85 | RIPK1 (0.40) | RIPK1PDE5ATP53MDM2MAOA | |
| SCHEMBL25324582 | 0.84 | DPP4 (0.36) | MDM2 | |
| SCHEMBL25327435 | 0.83 | RIPK1 (0.53) | RIPK1PDE5AKIF11ALOX5MAOA | |
| SCHEMBL25328377 | 0.80 | TMEM97 (0.45) | SLC6A9 | |
| SCHEMBL25326844 | 0.79 | RIPK1 (0.37) | RIPK1PDE5AMAOAMAOBSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |