Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | FASN | P49327 | 3/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700000 | 0.88 | MGLL (0.50) | MGLLDPP4FASNDPP7PRKAB2 | |
| SCHEMBL25323033 | 0.87 | MGLL (0.39) | MGLLFASNENPP2ATXN2 | |
| SCHEMBL25324932 | 0.87 | MGLL (0.40) | MGLLDPP4FASNDPP7PRKAB2 | |
| SCHEMBL31549740 | 0.80 | MGLL (0.40) | MGLLDPP4DPP7PRKAB2PRKAG1 | |
| SCHEMBL30700021 | 0.78 | MGLL (0.43) | MGLLFASNPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL25259801 | 0.74 | PRKAB2 (0.42) | MGLLDPP4DPP7PRKAB2PRKAG1 | |
| SCHEMBL30700353 | 0.74 | MGLL (0.50) | MGLLFASNPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL25326463 | 0.74 | MGLL (0.41) | MGLLFASNPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL30012727 | 0.74 | P2RX7 (0.37) | DPP4DPP7SLC6A9KCNH2 | |
| SCHEMBL27143693 | 0.74 | P2RX7 (0.37) | DPP4DPP7SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-03-27 | — | — | US | claimed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-03-27 | — | — | US | disclosed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | OPRM1, CYP1A1, CYP3A4 | MGLL 3523/4885DPP4 2629/4885FASN 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.