Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25324705 | 0.88 | SCD5 (0.38) | USP30SCD5BRD4CREBBP | |
| SCHEMBL24366022 | 0.88 | SCD5 (0.38) | USP30SCD5BRD4CREBBP | |
| SCHEMBL30886968 | 0.81 | GRM5 (0.37) | — | |
| SCHEMBL25914460 | 0.81 | GRM5 (0.37) | — | |
| SCHEMBL30886178 | 0.81 | GRM5 (0.37) | — | |
| SCHEMBL25324334 | 0.80 | PIK3CD (0.41) | USP30BRD4CREBBPBACE1BACE2 | |
| SCHEMBL25324329 | 0.80 | PIK3CD (0.41) | USP30BRD4CREBBPBACE1BACE2 | |
| SCHEMBL25321630 | 0.78 | TYK2 (0.34) | LPLLIPG | |
| SCHEMBL25321628 | 0.78 | TYK2 (0.34) | LPLLIPG | |
| SCHEMBL25323073 | 0.78 | LIPG (0.32) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |