SCHEMBL25328007

SCHEMBL25328007

CCS(=O)(=O)c1c(-c2ncc(-c3ccc(OC(F)(F)F)cc3)n2C)nc2ccc(C(F)(F)F)cn12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
TP53 P04637 2/20 0.38
GAA P10253 2/20 0.38
SCN5A Q14524 9/20 0.38
ATP1A1 P05023 1/20 0.37
ATP1B1 P05026 1/20 0.37
ATP1A3 P13637 1/20 0.37
ATP1B2 P14415 1/20 0.37
ATP1A2 P50993 1/20 0.37
ATP1B3 P54709 1/20 0.37
FXYD2 P54710 1/20 0.37
ATP1A4 Q13733 1/20 0.37
MCHR1 Q99705 1/20 0.35
POLB P06746 1/20 0.35
SCN1A P35498 2/20 0.34
SCN2A Q99250 2/20 0.34
PPARD Q03181 2/20 0.34
TDP2 O95551 1/20 0.34
TRPA1 O75762 1/20 0.34
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18751285 0.81 ATP1A1 (0.40) MAPTTP53GAASCN5AATP1A1
SCHEMBL24209128 0.80 TRPA1 (0.37) TRPA1KDM4EALDH1A1
SCHEMBL25326000 0.80 TRPA1 (0.37) POLBTRPA1KDM4EALDH1A1
SCHEMBL25911725 0.73 ATP1A1 (0.37) SCN5AATP1A1ATP1B1ATP1A3ATP1B2
SCHEMBL21550152 0.73 POLB (0.43) POLBTRPA1KDM4EALDH1A1
SCHEMBL19981424 0.73 ATP1A1 (0.42) MAPTGAAATP1A1ATP1B1ATP1A3
SCHEMBL24460210 0.72 SCN5A (0.60) SCN5ASCN1ASCN2A
SCHEMBL23950067 0.72 TNF (0.36) TRPA1
SCHEMBL21805957 0.72 TRPA1 (0.36) TRPA1PTGS2KDM4EALDH1A1
SCHEMBL31207155 0.72 TRPA1 (0.36) TRPA1PTGS2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357232-A1 IMIDAZO[1,2-A]PYRIDINE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2023-11-09 US disclosed
US-20230357232-A1 IMIDAZO[1,2-A]PYRIDINE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2023-11-09 US disclosed
EP-4219491-A1 IMIDAZO[1,2-A]PYRIDINE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2023-08-02 EP disclosed
WO-2022065235-A1 IMIDAZO[1,2-A]PYRIDINE COMPOUND AND PEST CONTROL AGENT 日本曹達株式会社 2022-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357232-A1 IMIDAZO[1,2-A]PYRIDINE COMPOUND AND PEST CONTROL AGENT CTRL, CBR3, ITPR3 MAPT 4580/4885TP53 4538/4885GAA 3044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.