Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746434 | 0.86 | MAPT (0.56) | CYP1A2SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL25915047 | 0.84 | MAPK1 (0.57) | CYP1A2SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL28746466 | 0.84 | TRPM8 (0.53) | CYP1A2SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL29565728 | 0.84 | TRPM8 (0.53) | CYP1A2SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL25328209 | 0.82 | KDM4E (0.56) | CYP1A2SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL25325875 | 0.81 | F11 (0.72) | SMN1; SMN2RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL27895954 | 0.81 | CYP1A2 (0.78) | CYP1A2SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL28746461 | 0.81 | MAPK1 (0.53) | CYP1A2SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL25326523 | 0.78 | KDM4E (0.47) | SMN1; SMN2RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL19301744 | 0.78 | MAPK1 (0.47) | CYP1A2SMN1; SMN2RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105881-B | Platelet aggregation inhibitor, and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114539158-B | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2023-12-08 | — | — | CN | disclosed |
| EP-3960734-B1 | PLATELET AGGREGATION INHIBITOR, PREPARATION AND USES THEREOF | SHENYANG HINEWY PHARMACEUTICAL TECH CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |
| EP-3960734-B1 | PLATELET AGGREGATION INHIBITOR, PREPARATION AND USES THEREOF | SHENYANG HINEWY PHARMACEUTICAL TECH CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |
| US-11713300-B2 | Platelet aggregation inhibitor, preparation and uses thereof | SHENYANG HINEWY PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-08-01 | — | — | US | disclosed |
| US-11713300-B2 | Platelet aggregation inhibitor, preparation and uses thereof | SHENYANG HINEWY PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-08-01 | — | — | US | disclosed |
| US-11713300-B2 | Platelet aggregation inhibitor, preparation and uses thereof | SHENYANG HINEWY PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713300-B2 | Platelet aggregation inhibitor, preparation and uses thereof | TFPI, F12, TFPI2 | CYP1A2 2238/4885SMN1; SMN2 2498/4885RAB9A 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.