Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746444 | 0.88 | F11 (0.48) | MAPK1PDE2APDE10AMAPTSMN1; SMN2 | |
| SCHEMBL29565489 | 0.88 | F11 (0.48) | MAPK1PDE2APDE10AMAPTSMN1; SMN2 | |
| SCHEMBL28746453 | 0.82 | LMNA (0.51) | MAPK1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL25326523 | 0.81 | KDM4E (0.47) | MAPK1MAPTSMN1; SMN2TP53RAB9A | |
| SCHEMBL25328154 | 0.81 | CYP1A2 (0.66) | MAPK1MAPTSMN1; SMN2TP53RAB9A | |
| SCHEMBL28746434 | 0.78 | MAPT (0.56) | MAPTSMN1; SMN2TP53RAB9AALDH1A1 | |
| SCHEMBL29565728 | 0.77 | TRPM8 (0.53) | MAPK1MAPTSMN1; SMN2TP53RAB9A | |
| SCHEMBL28746466 | 0.77 | TRPM8 (0.53) | MAPK1MAPTSMN1; SMN2TP53RAB9A | |
| SCHEMBL28746474 | 0.75 | MAPK1 (0.43) | MAPK1PDE2APDE10AMAPTSMN1; SMN2 | |
| SCHEMBL28800164 | 0.74 | PDE4B (0.55) | MAPK1PDE2APDE10AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539158-B | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-114539158-A | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2022-05-27 | — | — | CN | disclosed |