Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.54 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5937245 | 0.86 | GABRA2 (0.61) | MAPTKDM4EALDH1A1SMN1; SMN2GABRA2 | |
| SCHEMBL25328154 | 0.86 | CYP1A2 (0.66) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL29565728 | 0.84 | TRPM8 (0.53) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL28746466 | 0.84 | TRPM8 (0.53) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL25328209 | 0.83 | KDM4E (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL28746452 | 0.81 | CYP1A2 (0.58) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL4785430 | 0.80 | GABRA2 (0.48) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL28746461 | 0.78 | MAPK1 (0.53) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL25325869 | 0.77 | F11 (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL25327136 | 0.75 | F11 (0.73) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539158-B | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-114539158-A | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2022-05-27 | — | — | CN | disclosed |