Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 1.00 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.78 |
| ▸ | NQO2 | P16083 | 3/20 | 0.76 |
| ▸ | NQO1 | P15559 | 1/20 | 0.76 |
| ▸ | TTR | P02766 | 3/20 | 0.75 |
| ▸ | ABL1 | P00519 | 3/20 | 0.75 |
| ▸ | BCR | P11274 | 3/20 | 0.75 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.75 |
| ▸ | BACE1 | P56817 | 1/20 | 0.74 |
| ▸ | APP | P05067 | 3/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.72 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.72 |
| ▸ | MYC | P01106 | 1/20 | 0.72 |
| ▸ | TYR | P14679 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25328697 | 1.00 | ALOX5 (1.00) | ALOX5NFE2L2NQO2NQO1TTR | |
| SCHEMBL17732299 | 0.89 | TTR (0.85) | ALOX5NFE2L2TTRABCB1BACE1 | |
| SCHEMBL30807100 | 0.89 | TTR (0.85) | ALOX5NFE2L2TTRABCB1BACE1 | |
| SCHEMBL671149 | 0.89 | TTR (0.85) | ALOX5NFE2L2TTRABCB1BACE1 | |
| SCHEMBL671150 | 0.89 | TTR (0.85) | ALOX5NFE2L2TTRABCB1BACE1 | |
| SCHEMBL614483 | 0.88 | NFE2L2 (1.00) | ALOX5NFE2L2NQO2TTRAPP | |
| SCHEMBL614484 | 0.88 | NFE2L2 (1.00) | ALOX5NFE2L2NQO2TTRAPP | |
| SCHEMBL3127862 | 0.87 | ALOX5 (0.77) | ALOX5NFE2L2NQO2TTRABL1 | |
| SCHEMBL3127856 | 0.87 | ALOX5 (0.77) | ALOX5NFE2L2NQO2TTRABL1 | |
| SCHEMBL2966533 | 0.86 | ALOX5 (1.00) | ALOX5NQO2NQO1TTRABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12466784-B2 | Analogs of pterostilbene amino acid bearing carbonates for treating a non-alcoholic fatty liver disease and nonalcoholic steatohepatitis | APICAL MOLECULAR BIOTECH CO., LTD. (TW) | 2025-11-11 | — | — | US | disclosed |
| EP-4136063-B1 | NOVEL ANALOGS OF PTEROSTILBENE AMINO ACID BEARING CARBONATES FOR TREATING A NON-ALCOHOLIC FATTY LIVER DISEASE AND NONALCOHOLIC STEATOHEPATITIS | APICAL MOLECULAR BIOTECH CO LTD (TW) | 2025-10-22 | — | — | EP | disclosed |
| US-20230234912-A1 | NOVEL ANALOGS OF PTEROSTILBENE AMINO ACID BEARING CARBONATES FOR TREATING A NON-ALCOHOLIC FATTY LIVER DISEASE AND NONALCOHOLIC STEATOHEPATITIS | APICAL MOLECULAR BIOTECH CO., LTD. (TW) | 2023-07-27 | — | — | US | disclosed |
| CN-115835860-A | Novel analogues of pterostilbene amino acids with carbonate for the treatment of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis | 树顶分子生技股份有限公司 | 2023-03-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234912-A1 | NOVEL ANALOGS OF PTEROSTILBENE AMINO ACID BEARING CARBONATES FOR TREATING A NON-ALCOHOLIC FATTY LIVER DISEASE AND NONALCOHOLIC STEATOHEPATITIS | FABP1, GLS2, SLC1A5 | ALOX5 888/4885NFE2L2 2553/4885NQO2 4477/4885 |
| US-12466784-B2 | Analogs of pterostilbene amino acid bearing carbonates for treating a non-alcoholic fatty liver disease and nonalcoholic steatohepatitis | FABP1, GLS2, SLC1A5 | ALOX5 904/4885NFE2L2 2476/4885NQO2 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.