Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.78 |
| ▸ | RELA | Q04206 | 2/20 | 0.74 |
| ▸ | NQO2 | P16083 | 1/20 | 0.74 |
| ▸ | TTR | P02766 | 1/20 | 0.72 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.71 |
| ▸ | TUBB | P07437 | 2/20 | 0.71 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.71 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.71 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.71 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.71 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.71 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.71 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.71 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.71 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.71 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.71 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.71 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.71 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614483 | 1.00 | NFE2L2 (1.00) | NFE2L2ALOX5RELANQO2TTR | |
| SCHEMBL17732299 | 0.91 | TTR (0.85) | NFE2L2ALOX5RELATTRAPP | |
| SCHEMBL671149 | 0.91 | TTR (0.85) | NFE2L2ALOX5RELATTRAPP | |
| SCHEMBL30807100 | 0.91 | TTR (0.85) | NFE2L2ALOX5RELATTRAPP | |
| SCHEMBL671150 | 0.91 | TTR (0.85) | NFE2L2ALOX5RELATTRAPP | |
| SCHEMBL25328697 | 0.88 | ALOX5 (1.00) | NFE2L2ALOX5RELANQO2TTR | |
| SCHEMBL25328702 | 0.88 | ALOX5 (1.00) | NFE2L2ALOX5RELANQO2TTR | |
| SCHEMBL5315843 | 0.87 | TTR (0.80) | NFE2L2ALOX5RELATTRAPP | |
| SCHEMBL9616786 | 0.87 | TTR (0.80) | NFE2L2ALOX5RELATTRAPP | |
| SCHEMBL25206969 | 0.86 | CXCL12 (0.95) | NFE2L2CXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139650-A1 | Fungicidally Active Polymer Dispersions And Use Thereof | CELANESE EMULSIONS GMBH (DE) | 2008-06-12 | — | — | US | claimed |
| EP-1796459-A2 | FUNGICIDALLY ACTIVE POLYMER DISPERSIONS AND USE THEREOF | Celanese Emulsions GmbH (DE) | 2007-06-20 | — | — | EP | claimed |
| WO-2006034762-A2 | FUNGICIDALLY ACTIVE POLYMER DISPERSIONS AND USE THEREOF | CELANESE EMULSIONS GMBH (DE) | 2006-04-06 | — | — | WO | claimed |
| US-8981152-B2 | Microwave induced single step green synthesis of some novel 2-aryl aldehydes and their analogues | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-03-17 | — | — | US | disclosed |
| US-20140197024-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-07-17 | — | — | US | disclosed |
| US-8779200-B2 | Microwave induced single step green synthesis of some novel 2-aryl aldehydes and their analogues | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-07-15 | — | — | US | disclosed |
| US-8716532-B2 | One pot multicomponent synthesis of some novel hydroxy stilbene derivatives with alpha, beta-carbonyl conjugation under microwave irradiation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-05-06 | — | — | US | disclosed |
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-28 | — | — | US | disclosed |
| US-20120041234-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETIES ACT (ACT XXI OF 1860)) (IN) | 2012-02-16 | — | — | US | disclosed |
| WO-2010113005-A2 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010097811-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-02 | — | — | WO | disclosed |
| US-7759527-B2 | Microwave induced one pot process for the preparation of arylethenes | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-20 | — | — | US | disclosed |
| US-20080139650-A1 | Fungicidally Active Polymer Dispersions And Use Thereof | CELANESE EMULSIONS GMBH (DE) | 2008-06-12 | — | — | US | disclosed |
| US-20080045752-A1 | Microwave Induced One Pot Process For The Preparation Of Arylethenes | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-02-21 | — | — | US | disclosed |
| US-20070276172-A1 | Single step microwave induced process for the preparation of substituted stilbenes and its analogs | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-11-29 | — | — | US | disclosed |
| WO-2007110883-A1 | A SINGLE STEP MICROWAVE INDUCED PROCESS FOR THE PREPARATION OF SUBSTITUTED STILBENES AND ITS ANALOGS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-10-04 | — | — | WO | disclosed |
| WO-2007110881-A1 | A MICROWAVE INDUCED ONE POT PROCESS FOR THE PREPARATION OF ARYLETHENES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276172-A1 | Single step microwave induced process for the preparation of substituted stilbenes and its analogs | HRH3, HPD, TET2 | NFE2L2 2018/4885ALOX5 3390/4885RELA 1159/4885 |
| US-20080045752-A1 | Microwave Induced One Pot Process For The Preparation Of Arylethenes | TET2, HCN4, KDM4E | NFE2L2 732/4885ALOX5 2892/4885RELA 1472/4885 |
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | SIK1, SIK2, HCK | NFE2L2 237/4885ALOX5 3187/4885RELA 948/4885 |
| US-20080139650-A1 | Fungicidally Active Polymer Dispersions And Use Thereof | CBR3, CBR1, CYP3A4 | NFE2L2 3306/4885ALOX5 251/4885RELA 3212/4885 |
| US-20140197024-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | WFS1, EPHX2, MANBA | NFE2L2 5/4885ALOX5 492/4885RELA 2020/4885 |
| US-20120041234-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | AADAC, NAT1, CTRB1 | NFE2L2 567/4885ALOX5 377/4885RELA 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.