Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145421 | 0.84 | TSHR (0.43) | TSHRALDH1A1THRB | |
| SCHEMBL3886364 | 0.84 | TSHR (0.43) | TSHRALDH1A1THRB | |
| SCHEMBL5394202 | 0.81 | TSHR (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL9820071 | 0.80 | TSHR (0.37) | TSHRALDH1A1 | |
| SCHEMBL16537575 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1 | |
| SCHEMBL6925919 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1 | |
| SCHEMBL4196691 | 0.78 | TSHR (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL193159 | 0.77 | ALDH1A1 (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL10762910 | 0.77 | — | — | |
| SCHEMBL27553112 | 0.77 | TSHR (0.48) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148171-A1 | MULTIFUNCTIONAL CROSSLINKING AGENTS AND OPHTHALMIC DEVICES FORMED THEREFROM | BAUSCH + LOMB IRELAND LIMITED (IE) | 2023-08-10 | — | — | WO | disclosed |
| US-20230244000-A1 | MULTIFUNCTIONAL CROSSLINKING AGENTS AND OPHTHALMIC DEVICES FORMED THEREFROM | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT | 2023-08-03 | — | — | US | disclosed |