Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.39 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | GGH | Q92820 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4821084 | 0.75 | CYP1A2 (0.46) | FOLH1KEAP1NAALAD2RIMKLAGGH | |
| SCHEMBL1314840 | 0.74 | AAK1 (0.43) | AAK1KDM4EGAAALDH1A1 | |
| SCHEMBL28948390 | 0.74 | HPGDS (0.40) | FOLH1MMP8MMP13 | |
| SCHEMBL31520743 | 0.73 | AAK1 (0.48) | AAK1 | |
| SCHEMBL25928969 | 0.73 | AAK1 (0.48) | AAK1ALDH1A1 | |
| SCHEMBL22502529 | 0.73 | AAK1 (0.48) | AAK1ALDH1A1 | |
| SCHEMBL31444708 | 0.73 | AAK1 (0.48) | AAK1 | |
| SCHEMBL30493278 | 0.73 | AAK1 (0.48) | AAK1ALDH1A1 | |
| SCHEMBL5497074 | 0.72 | MAPK14 (0.48) | FOLH1 | |
| SCHEMBL4826994 | 0.72 | ALDH1A1 (0.44) | FOLH1KDM4ETDP1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |