Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | GART | P22102 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | GGH | Q92820 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5930500 | 0.87 | CYP1A2 (0.42) | CYP1A2MAPTCYP2C9CYP2C19KEAP1 | |
| SCHEMBL4821678 | 0.86 | MAPT (0.48) | CYP1A2MAPTCYP2C9CYP2C19KEAP1 | |
| SCHEMBL5930464 | 0.82 | MAPT (0.38) | CYP1A2MAPTCYP2C9CYP2C19KEAP1 | |
| SCHEMBL28008720 | 0.80 | ITGB3 (0.50) | KEAP1NAALAD2FOLH1RIMKLAGGH | |
| SCHEMBL11385642 | 0.78 | CA2 (0.51) | GARTNAALAD2FOLH1RIMKLACA2 | |
| SCHEMBL11385645 | 0.78 | CA2 (0.51) | GARTNAALAD2FOLH1RIMKLACA2 | |
| SCHEMBL5930493 | 0.77 | CA12 (0.42) | CYP1A2MAPTCYP2C9CYP2C19RAD52 | |
| SCHEMBL4829854 | 0.76 | L3MBTL1 (0.51) | CYP1A2MAPTCYP2C9CYP2C19RAD52 | |
| SCHEMBL4828335 | 0.76 | GGH (0.48) | NAALAD2FOLH1RIMKLAGGHCA2 | |
| SCHEMBL28535426 | 0.76 | GGH (0.48) | NAALAD2FOLH1RIMKLAGGHCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | claimed |
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | claimed |
| EP-1580186-A1 | Secondary p-phenylendiamines containing a carboxylic acid group, dye composition containing them, processes and uses | L'OREAL (FR) | 2005-09-28 | — | — | EP | claimed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
| EP-1580186-A1 | Secondary p-phenylendiamines containing a carboxylic acid group, dye composition containing them, processes and uses | L'OREAL (FR) | 2005-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | KRT18, CDC73, JUP | CYP1A2 1398/4885MAPT 1947/4885CYP2C9 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.