Sugi Predict

Sugi Predict / Compounds / SCHEMBL2533089

SCHEMBL2533089

SCHEMBL2533089

CCC(Cl)CCCCCO

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.43
▸ ALDH1A1 P00352 3/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ KDM4E B2RXH2 2/20 0.32
▸ CYP2D6 P10635 2/20 0.30
▸ SPHK1 Q9NYA1 1/20 0.30
▸ GMNN O75496 1/20 0.30
▸ POLB P06746 1/20 0.30
▸ THPO P40225 1/20 0.30
▸ MTOR P42345 1/20 0.30
▸ BLM P54132 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ CETP P11597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2535849 0.97 — —
SCHEMBL1741973 0.90 — —
SCHEMBL22071625 0.87 ALDH1A1 (0.35) LMNAALDH1A1TSHR
SCHEMBL2541006 0.84 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL2541675 0.84 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL2538612 0.84 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL2540561 0.84 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL18572711 0.83 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL2535101 0.81 SMN1; SMN2 (0.35) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL2537751 0.80 SMN1; SMN2 (0.46) LMNAALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114316102-B Alkoxy magnesium carrier, polyethylene catalyst and preparation method thereof 北京吉海川科技发展有限公司 2023-12-22 — — CN disclosed
CN-114316102-A Alkoxy magnesium carrier, polyethylene catalyst and preparation method thereof 北京吉海川科技发展有限公司 2022-04-12 — — CN disclosed
US-10786530-B2 Antimicrobial cationic polycarbonates INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-09-29 — — US disclosed
US-10712682-B2 Toner and image forming method Konica Minolta, Inc. (JP) 2020-07-14 — — US disclosed
US-20200073269-A1 TONER AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2020-03-05 — — US disclosed
US-9999633-B2 Antimicrobial cationic polycarbonates INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-06-19 — — US disclosed
US-9631050-B2 Antimicrobial cationic polycarbonates INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-04-25 — — US disclosed
US-20160257782-A1 ANTIMICROBIAL CATIONIC POLYCARBONATES INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-09-08 — — US disclosed
US-9357772-B2 Antimicrobial cationic polycarbonates INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-06-07 — — US disclosed
EP-2983679-A2 ANTIMICROBIAL CATIONIC POLYCARBONATES International Business Machines Corporation (US) 2016-02-17 — — EP disclosed
WO-2014168771-A2 ANTIMICROBIAL CATIONIC POLYCARBONATES INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-10-16 — — WO disclosed
WO-2014168762-A1 ANTIMICROBIAL CATIONIC POLYCARBONATES INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-10-16 — — WO disclosed
US-20140301968-A1 ANTIMICROBIAL CATIONIC POLYCARBONATES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-10-09 — — US disclosed
US-20140301967-A1 ANTIMICROBIAL CATIONIC POLYCARBONATES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-10-09 — — US disclosed
US-8044070-B2 Heteroaryloxy nitrogenous saturated heterocyclic derivative MSD K.K. (JP) 2011-10-25 — — US disclosed
US-20100210637-A1 HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE MSD K.K. (JP) 2010-08-19 — — US disclosed
US-7595316-B2 Heteroaryloxy nitrogenous saturated heterocyclic derivative BANYU PHARMACEUTICAL CO., LTD. (JP) 2009-09-29 — — US disclosed
US-20060178375-A1 Heteroaryloxy nitrogenous saturated heterocyclic derivative MSD K.K. (JP) 2006-08-10 — — US disclosed
EP-1642898-A1 HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-04-05 — — EP disclosed
US-5804097-A HAVING HIGH FLOW VISCOSITY, GOOD MISCIBILITY WITH OTHER LIQUID CRYSTALS BASF AKTIENGSELLSCHAFT (DE) 1998-09-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140301967-A1 ANTIMICROBIAL CATIONIC POLYCARBONATES VDR, GC, CYP24A1 LMNA 2404/4885ALDH1A1 4827/4885HSD17B10 636/4885
US-20160257782-A1 ANTIMICROBIAL CATIONIC POLYCARBONATES VDR, GC, CYP24A1 LMNA 2404/4885ALDH1A1 4827/4885HSD17B10 636/4885
US-20140301968-A1 ANTIMICROBIAL CATIONIC POLYCARBONATES VDR, GC, CYP24A1 LMNA 2404/4885ALDH1A1 4827/4885HSD17B10 636/4885
US-20060178375-A1 Heteroaryloxy nitrogenous saturated heterocyclic derivative HRH3, HRH4, HCRTR2 LMNA 3909/4885ALDH1A1 3756/4885HSD17B10 836/4885
US-20100210637-A1 HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE HRH3, HRH4, HRH2 LMNA 3913/4885ALDH1A1 2837/4885HSD17B10 923/4885
US-10786530-B2 Antimicrobial cationic polycarbonates VDR, GC, CYP24A1 LMNA 2404/4885ALDH1A1 4827/4885HSD17B10 636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.