⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20488986 | 1.00 | — | — | |
| SCHEMBL25364272 | 0.87 | ALDH1A1 (0.32) | — | |
| SCHEMBL21790282 | 0.87 | ALDH1A1 (0.32) | — | |
| SCHEMBL22283170 | 0.81 | — | — | |
| SCHEMBL25365621 | 0.81 | — | — | |
| SCHEMBL25365895 | 0.78 | — | — | |
| SCHEMBL4972513 | 0.75 | FKBP1A (0.33) | — | |
| SCHEMBL25335802 | 0.75 | RORC (0.31) | — | |
| SCHEMBL20488133 | 0.75 | RORC (0.31) | — | |
| SCHEMBL4214203 | 0.75 | FKBP1A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023133174-A1 | PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION | MERCK SHARP & DOHME LLC (US) | 2023-07-13 | — | — | WO | disclosed |