Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20488133 | 1.00 | RORC (0.31) | RORCPDK2POLBL3MBTL1 | |
| SCHEMBL21790284 | 0.79 | NR1H2 (0.38) | — | |
| SCHEMBL25366788 | 0.79 | NR1H2 (0.38) | — | |
| SCHEMBL25335347 | 0.76 | ATM (0.33) | — | |
| SCHEMBL13858417 | 0.75 | RIPK1 (0.42) | RORCPOLBL3MBTL1 | |
| SCHEMBL15320412 | 0.75 | RIPK1 (0.42) | RORCPOLBL3MBTL1 | |
| SCHEMBL16992110 | 0.75 | RIPK1 (0.42) | RORCPOLBL3MBTL1 | |
| SCHEMBL25333045 | 0.75 | — | — | |
| SCHEMBL20488986 | 0.75 | — | — | |
| SCHEMBL16774688 | 0.74 | POLB (0.32) | POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023133174-A1 | PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION | MERCK SHARP & DOHME LLC (US) | 2023-07-13 | — | — | WO | disclosed |