Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.40 |
| ▸ | RELA | Q04206 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675115 | 0.79 | NOTUM (0.45) | SLC6A2SLC6A4GAAGFERNOTUM | |
| SCHEMBL27463313 | 0.76 | ALDH1A1 (0.42) | SLC6A2SLC6A4GAAGFERNOTUM | |
| SCHEMBL19953534 | 0.76 | MEN1 (0.42) | SLC6A2SLC6A4GAAGFERNOTUM | |
| SCHEMBL25333374 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4GAAGFERNOTUM | |
| SCHEMBL28292118 | 0.73 | MAPT (0.48) | SLC6A2SLC6A4GAANOTUMMAPT | |
| SCHEMBL27675111 | 0.72 | GAA (0.56) | SLC6A2SLC6A4GAAGFERNOTUM | |
| SCHEMBL1102007 | 0.72 | ALDH1A1 (0.48) | SLC6A2SLC6A4GAAGFERNOTUM | |
| SCHEMBL28647947 | 0.72 | ALDH1A1 (0.42) | SLC6A2SLC6A4GAAGFERNOTUM | |
| SCHEMBL28292859 | 0.72 | ALDH1A1 (0.42) | SLC6A2SLC6A4GAAGFERNOTUM | |
| SCHEMBL27342036 | 0.72 | ALDH1A1 (0.42) | SLC6A2SLC6A4GAAGFERNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021156774-A1 | COMBINATION THERAPY FOR TREATING MPS1 | GAIN THERAPEUTICS SA (CH) | 2021-08-12 | — | — | WO | disclosed |