Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL7945124 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL720025 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL327041 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL8443332 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL8001130 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL5786102 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL11133018 | 0.93 | LMNA (0.60) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL28097673 | 0.93 | LMNA (0.60) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL27864060 | 0.93 | LMNA (0.60) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL11133021 | 0.93 | LMNA (0.60) | LMNAALDH1A1THRBCA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102695686-B | Hardening accelerator for hydraulic composition | KAO CORP | 2015-04-01 | — | — | CN | claimed |
| EP-4356897-A1 | POWDER COSMETIC AND PRODUCTION METHOD FOR SAME | Shiseido Company, Ltd. (JP) | 2024-04-24 | — | — | EP | disclosed |
| CN-102888110-B | Manufacturing method of polyphenylene sulfide composite granules containing toughening material | 四川得阳特种新材料有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-102888111-B | Manufacturing method of polyphenylene sulfide ceramic alloy | 四川得阳特种新材料有限公司 | 2024-01-16 | — | — | CN | disclosed |
| WO-2023219108-A1 | OIL-IN-WATER COMPOSITION | 株式会社 資生堂 | 2023-11-16 | — | — | WO | disclosed |
| WO-2023162789-A1 | COMPOSITION, FILM, METHOD FOR PRODUCING FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND STRUCTURE | 富士フイルム株式会社 | 2023-08-31 | — | — | WO | disclosed |
| WO-2022202766-A1 | CLEANING COMPOSITION | ロート製薬株式会社 | 2022-09-29 | — | — | WO | disclosed |
| CN-114846108-A | Anti-pollution material | 日产化学株式会社 | 2022-08-02 | — | — | CN | disclosed |
| CN-110123669-B | Oral composition containing metal ions | 高露洁-棕榄公司 | 2022-06-03 | — | — | CN | disclosed |
| WO-2022092284-A1 | COMPOSITION CONTAINING LIPID PEPTIDE AND SUCROSE ESTER | 日産化学株式会社 | 2022-05-05 | — | — | WO | disclosed |
| CN-1275902-A | Hair care compositions comprising optical brighteners and non-volatile solvents | PROCTER & GAMBLE (US) | 2000-12-06 | — | — | CN | disclosed |
| CN-1054507-C | Improved intravaginal treatment of vaginal infections with buffered metranidazole compositions | CURATEK PHARMACEUTICALS LTD PA (US) | 2000-07-19 | — | — | CN | disclosed |
| CN-1246660-A | Usage of aluminum azo-complex dye as charge control agent | CLARIANT GMBH (DE) | 2000-03-08 | — | — | CN | disclosed |
| CN-1219862-A | Conditioning shampoo compositions | PROCTER & GAMBLE (US) | 1999-06-16 | — | — | CN | disclosed |
| CN-1029856-C | Mild skin cleansing toilet bar with silicone skin mildness/moisturizing aid | PROCTER & GAMBLE (US) | 1995-09-27 | — | — | CN | disclosed |
| CN-1078251-A | Neutral pH freezer bar and manufacture method thereof | PROCTER & GAMBLE (US) | 1993-11-10 | — | — | CN | disclosed |
| CN-1074237-A | Bleach activation | UNILEVER NV (NL) | 1993-07-14 | — | — | CN | disclosed |
| CN-1062373-A | The clean skin perfumed soap of mild that contains siloxanes skin gentleness/moisturizing aid | PROCTER & GAMBLE (US) | 1992-07-01 | — | — | CN | disclosed |
| CN-1049101-A | Improved with the method for buffering metronidazole compositions at intravaginal treatment vaginal infection | CURATEK PHARMACEUTICALS LTD PA (US) | 1991-02-13 | — | — | CN | disclosed |
| CN-1032488-A | Shampoo Compositions and preparation thereof | PROCTER & GAMBLE (US) | 1989-04-26 | — | — | CN | disclosed |