Glycerin

Glycerin

SCHEMBL720025

O=S(=O)(O)O.O=S(=O)(O)O.OCC(O)CO

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.64
ALDH1A1 P00352 1/20 0.64
CA5A P35218 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
THRB P10828 1/20 0.42
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 2/20 0.33
OR51E2 Q9H255 1/20 0.33
AKR1B1 P15121 1/20 0.33
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
BLM P54132 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL8443332 1.00 LMNA (0.64) LMNAALDH1A1CA5ACA5BTHRB
Glycerin SCHEMBL5786102 1.00 LMNA (0.64) LMNAALDH1A1CA5ACA5BTHRB
Glycerin SCHEMBL7945124 1.00 LMNA (0.64) LMNAALDH1A1CA5ACA5BTHRB
Glycerin SCHEMBL327041 1.00 LMNA (0.64) LMNAALDH1A1CA5ACA5BTHRB
Glycerin SCHEMBL8001130 1.00 LMNA (0.64) LMNAALDH1A1CA5ACA5BTHRB
Glycerin SCHEMBL11133018 0.97 LMNA (0.60) LMNAALDH1A1CA5ACA5BTHRB
Glycerin SCHEMBL28097673 0.97 LMNA (0.60) LMNAALDH1A1CA5ACA5BTHRB
Glycerin SCHEMBL27864060 0.97 LMNA (0.60) LMNAALDH1A1CA5ACA5BTHRB
Glycerin SCHEMBL11133021 0.97 LMNA (0.60) LMNAALDH1A1CA5ACA5BTHRB
Glycerin SCHEMBL2533377 0.97 LMNA (0.60) LMNAALDH1A1CA5ACA5BTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1421169-B1 ENCAPSULATED ACTIVE INGREDIENT PREPARATION FOR USE IN PARTICULATE DETERGENTS AND CLEANING AGENTS HENKEL KGAA (DE) 2006-07-26 EP claimed
US-6979669-B2 Encapsulated active ingredient preparation for use in particulate detergents and cleaning agents HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-12-27 US claimed
US-20040198629-A1 Encapsulated active ingredient preparation for use in particulate detergents and cleaning agents HENKEL AG & CO. KGAA (DE) 2004-10-07 US claimed
EP-4623057-A1 ENCAPSULATED FRAGRANCE COMPOSITIONS FOR PROVIDING, MODULATING OR INTENSIFYING A SCENT Symrise AG (DE) 2025-10-01 EP disclosed
WO-2025119505-A1 ENCAPSULATED FRAGRANCE COMPOSITIONS FOR PROVIDING, MODULATING OR INTENSIFYING A SCENT SYMRISE AG (DE) 2025-06-12 WO disclosed
US-20250179394-A1 MULTILAYER SYSTEM COMPRISING COMPOSITIONS HAVING SPECIFIC PERFUME COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2025-06-05 US disclosed
US-20250179395-A1 BLOOMING COEFFICIENT HENKEL AG & CO. KGAA (DE) 2025-06-05 US disclosed
EP-3771742-B1 TOILET BLOCK WITH IMPROVED SHINE HENKEL AG & CO KGAA (DE) 2025-05-28 EP disclosed
US-12312560-B2 Toilet rim block having an improved gloss HENKEL AG & CO. KGAA (DE) 2025-05-27 US disclosed
WO-2025103667-A1 CLEANING AGENT CONTAINING PROTEASE HENKEL AG & CO. KGAA (DE) 2025-05-22 WO disclosed
EP-3545012-B1 COPOLYMERS AND THEIR USE IN DETERGENT COMPOSITIONS CLARIANT INT LTD (CH) 2025-03-12 EP disclosed
US-7446086-B2 Agents that are absorbed on the surfaces of substrates HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-11-04 US disclosed
US-20080221003-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-09-11 US disclosed
US-20080207481-A1 CONSUMER PRODUCTS HAVING VARYING ODORS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-28 US disclosed
US-20080050398-A1 Composition Comprising Beta-Defensin 2 HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2008-02-28 US disclosed
EP-1781717-A1 COPOLYMER-CONTAINING CLEANING COMPOSITIONS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-05-09 EP disclosed
US-20060229230-A1 Agents that are absorbed on the surfaces of substrates HENKEL AG & CO. KGAA (DE) 2006-10-12 US disclosed
WO-2006005358-A1 COPOLYMER-CONTAINING CLEANING COMPOSITIONS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-01-19 WO disclosed
US-6979669-B2 Encapsulated active ingredient preparation for use in particulate detergents and cleaning agents HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-12-27 US disclosed
US-20040198629-A1 Encapsulated active ingredient preparation for use in particulate detergents and cleaning agents HENKEL AG & CO. KGAA (DE) 2004-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080050398-A1 Composition Comprising Beta-Defensin 2 DLK1, DSG1, DBNL LMNA 3080/4885ALDH1A1 2395/4885CA5A 4446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.