Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL8443332 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL5786102 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL720025 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL7945124 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL8001130 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL327041 | 0.97 | LMNA (0.64) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL28447409 | 0.94 | LMNA (0.53) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL11133018 | 0.93 | LMNA (0.60) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL11133021 | 0.93 | LMNA (0.60) | LMNAALDH1A1THRBCA5ACA5B | |
| Glycerin SCHEMBL2533377 | 0.93 | LMNA (0.60) | LMNAALDH1A1THRBCA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334617-B | Carboxyalkylated starch polyacrylic acid salt composite through compound base amount method | 阿彻丹尼尔斯米德兰德公司 | 2016-09-14 | — | — | CN | disclosed |