Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 3/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24765340 | 0.95 | ACE (0.51) | ACENPSR1MMEACE2ECE1 | |
| SCHEMBL24765356 | 0.95 | ACE (0.51) | ACENPSR1MMEACE2ECE1 | |
| SCHEMBL24764553 | 0.90 | CTSB (0.54) | ACEMMEACE2CPA1 | |
| SCHEMBL24765225 | 0.90 | CTSB (0.54) | ACEMMEACE2CPA1 | |
| SCHEMBL24765349 | 0.85 | CTSS (0.53) | ACEMMEECE1KMT2A | |
| SCHEMBL24765350 | 0.85 | CTSS (0.53) | ACEMMEECE1KMT2A | |
| SCHEMBL19974071 | 0.83 | L3MBTL1 (0.60) | ACENPSR1MMEACE2ECE1 | |
| SCHEMBL14456823 | 0.83 | L3MBTL1 (0.60) | ACENPSR1MMEACE2ECE1 | |
| SCHEMBL23572653 | 0.82 | OPRD1 (0.51) | ACE | |
| SCHEMBL23572652 | 0.82 | OPRD1 (0.51) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143351-A1 | DRUG CONJUGATE OF GLUCOCORTICOID | 上海盛迪医药有限公司 | 2023-08-03 | — | — | WO | disclosed |