SCHEMBL2533558

SCHEMBL2533558

C=COC(=O)c1ccncc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.53
NAPRT Q6XQN6 1/20 0.46
SNCA P37840 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
ALDH1A1 P00352 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KDM4E B2RXH2 4/20 0.42
RAB9A P51151 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
GLA P06280 1/20 0.42
TSHR P16473 1/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.41
MPO P05164 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295796 0.84 ALDH1A1 (0.40) SNCALMNAALDH1A1KMT2ATSHR
SCHEMBL28944014 0.82 ALDH1A1 (0.39) SNCALMNAALDH1A1KMT2ATSHR
SCHEMBL3962871 0.81 HSD17B10 (0.55) HSD17B10NAPRTSMN1; SMN2LMNACYP1A2
SCHEMBL9212492 0.79 HSD17B10 (0.53) HSD17B10NAPRTSMN1; SMN2LMNACYP1A2
SCHEMBL19506902 0.78 PDCD1 (0.41) SMN1; SMN2LMNAALDH1A1KDM4E
Benzoic Acid Vinyl Ester SCHEMBL28106984 0.78 LMNA (0.56) HSD17B10NAPRTSMN1; SMN2LMNAALDH1A1
Benzoic Acid Vinyl Ester SCHEMBL14903 0.78 LMNA (0.56) HSD17B10NAPRTSMN1; SMN2LMNAALDH1A1
SCHEMBL2531432 0.77 ALDH1A1 (0.61) LMNACYP1A2CYP2C19CYP2C9ALDH1A1
Benzoic Acid Vinyl Ester SCHEMBL6552669 0.77 LMNA (0.54) HSD17B10NAPRTSMN1; SMN2LMNAALDH1A1
Benzoic Acid Vinyl Ester SCHEMBL2909961 0.77 LMNA (0.54) HSD17B10NAPRTSMN1; SMN2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406834-B2 Material for forming passivation film for semiconductor substrate, passivation film for semiconductor substrate and method of producing the same, and photovoltaic cell element and method of producing the same HITACHI CHEMICAL COMPANY, LTD. (JP) 2016-08-02 US disclosed
US-20140242741-A1 MATERIAL FOR FORMING PASSIVATION FILM FOR SEMICONDUCTOR SUBSTRATE, PASSIVATION FILM FOR SEMICONDUCTOR SUBSTRATE AND METHOD OF PRODUCING THE SAME, AND PHOTOVOLTAIC CELL ELEMENT AND METHOD OF PRODUCING THE SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2014-08-28 US disclosed
US-8748877-B2 Material for forming passivation film for semiconductor substrate, passivation film for semiconductor substrate and method of producing the same, and photovoltaic cell element and method of producing the same HITACHI CHEMICAL COMPANY, LTD. (JP) 2014-06-10 US disclosed
US-20120313199-A1 MATERIAL FOR FORMING PASSIVATION FILM FOR SEMICONDUCTOR SUBSTRATE, PASSIVATION FILM FOR SEMICONDUCTOR SUBSTRATE AND METHOD OF PRODUCING THE SAME, AND PHOTOVOLTAIC CELL ELEMENT AND METHOD OF PRODUCING THE SAME HITACHI CHEMICAL COMPANY, LTD. 2012-12-13 US disclosed
US-8044233-B2 Process for preparing vinyl carboxylates BASF AKTIENGESELLSCHAFT (DE) 2011-10-25 US disclosed
US-20080308765-A1 Process for Preparing Vinyl Carboxylates BASF SE (DE) 2008-12-18 US disclosed
US-20080003288-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2008-01-03 US disclosed
US-7204997-B2 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2007-04-17 US disclosed
EP-1243579-B1 PROCESS FOR THE PRODUCTION OF PYRIDINE DERIVATIVES SANKIO CHEMICAL CO LTD (JP) 2005-01-26 EP disclosed
EP-1478403-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA, INC. (CA) 2004-11-24 EP disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed
US-6509469-B1 Reacting 1,2,4-triazine compound with vinyl carboxylate SANKIO CHEMICAL CO., LTD. (JP) 2003-01-21 US disclosed
EP-1243579-A1 PROCESS FOR THE PRODUCTION OF PYRIDINE DERIVATIVES Sankio Chemical Co., Ltd. (JP) 2002-09-25 EP disclosed
EP-0711813-B1 Antifouling coating composition HITACHI CHEMICAL CO LTD (JP) 2001-07-25 EP disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
US-5773508-A BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-06-30 US disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
EP-0711813-A2 Coating varnish composition and antifouling coating composition Hitachi Chemical Co., Ltd. (JP) 1996-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080308765-A1 Process for Preparing Vinyl Carboxylates MVD, MMAB, CRBN HSD17B10 727/4885NAPRT 3678/4885SNCA 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.