Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2538500 | 0.85 | — | — | |
| SCHEMBL27479392 | 0.82 | — | — | |
| SCHEMBL396072 | 0.80 | LMNA (0.33) | LMNAFAAHCA1CA2CYP1A2 | |
| SCHEMBL2535824 | 0.77 | GABRA1 (0.30) | CA2GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL396073 | 0.77 | FAAH (0.32) | LMNAFAAHCA1CA2CYP1A2 | |
| SCHEMBL2535831 | 0.76 | PDCD1 (0.30) | — | |
| SCHEMBL4083626 | 0.76 | LMNA (0.33) | LMNAFAAHCA1CA2CYP1A2 | |
| SCHEMBL7632473 | 0.75 | LMNA (0.31) | LMNAFAAHCA1CA2CYP1A2 | |
| SCHEMBL818811 | 0.74 | LMNA (0.33) | LMNAFAAHCA1CA2CYP1A2 | |
| SCHEMBL5613023 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044155-B2 | Coordination polymerization catalyst containing magnesium compound, titanium compound and organoaluminum compound | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2011-10-25 | — | — | US | disclosed |
| EP-1716185-B1 | Titanocene-based catalyst system | STICHTING DUTCH POLYMER INST (NL) | 2009-10-21 | — | — | EP | disclosed |
| US-20080234452-A1 | TITANOCENE-BASED CATALYST SYSTEM | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2008-09-25 | — | — | US | disclosed |
| US-20070179049-A1 | Titanocenen-based catalyst system | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2007-08-02 | — | — | US | disclosed |
| EP-1716185-A1 | TITANOCENE-BASED CATALYST SYSTEM | Stichting Dutch Polymer Institute (NL) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005077989-A1 | TITANOCENEN-BASED CATALYST SYSTEM | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2005-08-25 | — | — | WO | disclosed |
| EP-1564226-A1 | Titanocene-based catalyst system | Stichting Dutch Polymer Institute (NL) | 2005-08-17 | — | — | EP | disclosed |