SCHEMBL4083626

SCHEMBL4083626

CC1=Cc2c(C(C)C)cccc2C1[Zr](Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
FAAH O00519 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
GABRB1 P18505 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
HTR2B P41595 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7805739 0.85 GABRA1 (0.34) LMNAGABRA1GABRG2GABRB3FAAH
SCHEMBL7074605 0.83
SCHEMBL5721633 0.82 FAAH (0.31) LMNAGABRA1GABRG2GABRB3FAAH
SCHEMBL5788443 0.81 FAAH (0.32) LMNAGABRA1GABRG2GABRB3FAAH
SCHEMBL5721543 0.81 DHFR (0.31) CA1CA2
SCHEMBL4946930 0.80 MEN1 (0.32)
SCHEMBL5583462 0.79 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL5721331 0.78
SCHEMBL5721286 0.78 CA12 (0.32) CA1CA2TSHR
SCHEMBL5616374 0.77 PBRM1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104558340-A Propylene polymer with polar groups and preparation method of propylene polymer CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
EP-0530647-B1 Metallocenes, catalysts containing these and process for the manufacture of olefinic polymers by using these catalysts HOECHST AG (DE) 1998-01-28 EP claimed
US-5329033-A Metallocene catalyst, indene containing ligands, alumoxane cocatalyst HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-12 US claimed
CN-117946309-A Polymerization method of polybutene-1 and preparation method of polybutene-1 resin 中国石油化工股份有限公司 2024-04-30 CN disclosed
CN-103387623-B A kind of polymerizing reactor and application thereof SINOPEC CORP. (CN) 2015-08-19 CN disclosed
CN-103387624-B Preparation method of olefin polymer CHINA PETROLEUM & CHEMICAL 2015-06-17 CN disclosed
CN-104558340-A Propylene polymer with polar groups and preparation method of propylene polymer CHINA PETROLEUM & CHEMICAL 2015-04-29 CN disclosed
CN-103044599-B Propylene copolymer and film product CHINA PETROLEUM & CHEMICAL 2014-12-31 CN disclosed
WO-2009104783-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (2) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104785-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
US-7195129-B2 Inner container for household devices BASELL POLYOLEFINE GMBH (DE) 2007-03-27 US disclosed
EP-1263847-A1 PROCESS FOR THE PREPARATION OF ADDITIVE COATED MOLDING POWDER Borealis Technology Oy (FI) 2002-12-11 EP disclosed
US-20020013217-A1 CATALYST FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR ITS PREPARATION AND ITS USE HANS-FRIEDRICH HERRMANN 2002-01-31 US disclosed
US-20010021755-A1 Metallocenes containing aryl-substituted indenyl derivatives as ligands, process for their preparation, and their use as catalysts KUBER FRANK (DE) 2001-09-13 US disclosed
WO-2001062832-A1 PROCESS FOR THE PREPARATION OF ADDITIVE COATED MOLDING POWDER BOREALIS TECHNOLOGY OY (FI) 2001-08-30 WO disclosed
EP-1123319-A2 SUPPORTED POLYMERIZATION CATALYSTS Borealis Technology (FI) 2001-08-16 EP disclosed
US-20010007009-A1 Transition metal catalyzed polymerization of olefinic monomers in a water-containing polymerization medium BASF AKTIENGESELLSCHAFT (DE) 2001-07-05 US disclosed
WO-2000022011-A2 SUPPORTED POLYMERIZATION CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2000-04-20 WO disclosed
US-5770753-A ADDITION POLYMERIZATION CATALYST TARGOR GMBH (DE) 1998-06-23 US disclosed
US-5543377-A COMPRISING GROUP IVB TRANSITION METAL COMPOUND CONTAINING CYCLOPENTADIENYL LIGAND, ALUMINOXANE, KETOALCOHOL OR BETA-DIKETONE MITSUI PETROCHEMICAL INDUSTRIES CO., LTD. (JP) 1996-08-06 US disclosed