Hydroxytoluic Acid

Hydroxytoluic Acid

SCHEMBL25337502

Cc1cccc(C(=O)O)c1O.[NaH]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.96
KDM4E B2RXH2 4/20 0.96
HPGD P15428 3/20 0.96
HSD17B10 Q99714 2/20 0.96
CYP3A4 P08684 2/20 0.72
CYP2C9 P11712 2/20 0.72
KMT2A Q03164 2/20 0.72
ALB P02768 1/20 0.55
MMP2 P08253 1/20 0.55
MYC P01106 1/20 0.55
TRPA1 O75762 2/20 0.53
NAPRT Q6XQN6 2/20 0.53
MEN1 O00255 1/20 0.53
AKR1B10 O60218 1/20 0.53
ABCB11 O95342 1/20 0.53
DHFR P00374 1/20 0.53
LMNA P02545 1/20 0.53
MPO P05164 1/20 0.53
CYP1A2 P05177 1/20 0.53
CHRM1 P11229 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxytoluic Acid SCHEMBL8352264 0.98 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL29499765 0.98 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL25756 0.98 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL28037743 0.98 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL11527547 0.96 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL31174935 0.96 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL30538816 0.96 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL238307 0.96 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL25338040 0.96 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL622892 0.96 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102961364-A Sensitive and color-changing anti-acne repairing diaphragm SHANGHAI BIOTECH CO LTD 2013-03-13 CN claimed
CN-102579387-A Pharmaceutical compositions comprising an S1P modulator NOVARTIS AG 2012-07-18 CN claimed
CN-101516345-A Pharmaceutical compositions comprising S1P modulators NOVARTIS AG (CH) 2009-08-26 CN claimed
CN-1080118-C Freeze-dried ondanstetron compositions GLAXO WELLCOME INC (CA) 2002-03-06 CN claimed
CN-1171741-A Freeze-dried ondansetron compositions GLAXO WELLCOME INC (CA) 1998-01-28 CN claimed
US-20230251277-A1 METHOD FOR DETERMINING THE LEVEL OF VITAMIN D AND METABOLITES THEREOF ROCHE DIAGNOSTICS OPERATIONS, INC. 2023-08-10 US disclosed
EP-4222502-A1 A METHOD FOR DETERMINING THE LEVEL OF VITAMIN D AND METABOLITES THEREOF F. Hoffmann-La Roche AG (CH) 2023-08-09 EP disclosed
CN-203123075-U Photochromic anti-acne repair membrane sheet TCI SHANGHAI CO LTD 2013-08-14 CN disclosed
CN-102961364-A Sensitive and color-changing anti-acne repairing diaphragm SHANGHAI BIOTECH CO LTD 2013-03-13 CN disclosed
CN-102579387-A Pharmaceutical compositions comprising an S1P modulator NOVARTIS AG 2012-07-18 CN disclosed
CN-101516345-A Pharmaceutical compositions comprising S1P modulators NOVARTIS AG (CH) 2009-08-26 CN disclosed
CN-100512877-C Germ-free medicinal compositions ZENECA LTD (GB) 2009-07-15 CN disclosed
CN-1106192-C Oil-in-water emulsion containing 2, 6-diisopropyl phenol and ethylenediamine tetraacetate ZENECA LTD (GB) 2003-04-23 CN disclosed
CN-1080118-C Freeze-dried ondanstetron compositions GLAXO WELLCOME INC (CA) 2002-03-06 CN disclosed
CN-1309651-A Morpholine ethers GLAXO WELLCOME SA (ES) 2001-08-22 CN disclosed
CN-1058002-C Method for treatment of mixture of hydroperoxide SUMITOMO CHEMICAL CO (JP) 2000-11-01 CN disclosed
CN-1235014-A Use of 1,2-pentanediol in cosmetic or dermatological composition containing aqueous dispersion of film-forming polymer particles, and cosmetic or dermatological composition comprising these constituen OREAL (FR) 1999-11-17 CN disclosed
CN-1177922-A Oil-in-water emulsion containing 2, 6-diisopropyl phenol and ethylenediamine tetraacetate ZENECA LTD (GB) 1998-04-01 CN disclosed
CN-1171741-A Freeze-dried ondansetron compositions GLAXO WELLCOME INC (CA) 1998-01-28 CN disclosed
CN-1128754-A Method for treatment of mixture of hydroperoxide SUMITOMO CHEMICAL CO (JP) 1996-08-14 CN disclosed