Hydroxytoluic Acid

Hydroxytoluic Acid

SCHEMBL622892

Cc1cccc(C(=O)O)c1O.[Cu]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.96
KDM4E B2RXH2 4/20 0.96
HPGD P15428 3/20 0.96
HSD17B10 Q99714 2/20 0.96
CYP3A4 P08684 2/20 0.72
CYP2C9 P11712 2/20 0.72
KMT2A Q03164 2/20 0.72
ALB P02768 1/20 0.55
MMP2 P08253 1/20 0.55
MYC P01106 1/20 0.55
TRPA1 O75762 2/20 0.53
NAPRT Q6XQN6 2/20 0.53
MEN1 O00255 1/20 0.53
AKR1B10 O60218 1/20 0.53
ABCB11 O95342 1/20 0.53
DHFR P00374 1/20 0.53
LMNA P02545 1/20 0.53
MPO P05164 1/20 0.53
CYP1A2 P05177 1/20 0.53
CHRM1 P11229 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxytoluic Acid SCHEMBL30538824 1.00 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL25756 0.98 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL29499765 0.98 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL8352264 0.98 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL28037743 0.98 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL25337502 0.96 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL11527547 0.96 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL31174935 0.96 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL25338040 0.96 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL238307 0.96 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024354-B Preparation method of Rui Mi Buti Ni 天津凯莱英制药有限公司 2023-12-08 CN claimed
CN-117024354-A Preparation method of Rui Mi Buti Ni 天津凯莱英制药有限公司 2023-11-10 CN claimed
CN-114989399-B Room temperature Suzuki cross-coupling polymerization method of conjugated polymer semiconductor material 中国科学院大学 2023-08-01 CN claimed
US-9060511-B2 Compositions of dibromomalanomide and their use as biocides ROHM AND HAAS COMPANY (US) 2015-06-23 US claimed
EP-2582238-B1 COMPOSITIONS OF DIBROMOMALONAMIDE AND THEIR USE AS BIOCIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2014-06-04 EP claimed
US-20130142886-A1 COMPOSITIONS OF DIBROMOMALANOMIDE AND THEIR USE AS BIOCIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US claimed
EP-2582238-A1 COMPOSITIONS OF DIBROMOMALONAMIDE AND THEIR USE AS BIOCIDES Dow Global Technologies LLC (US) 2013-04-24 EP claimed
WO-2012021340-A1 COMPOSITIONS OF DIBROMOMALONAMIDE AND THEIR USE AS BIOCIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2012-02-16 WO claimed
CN-119768164-A Pharmaceutical compounds for treating complement-mediated disorders 阿雷克森制药公司 2025-04-04 CN disclosed
CN-119306724-A Bicyclic substituted pyridazine derivative and application thereof 正大天晴药业集团股份有限公司 2025-01-14 CN disclosed
CN-118525017-A Quinoline compounds as KRAS inhibitors 因赛特公司 2024-08-20 CN disclosed
WO-2024080317-A1 METHOD FOR PRODUCING HYDROXYBIOTIN DERIVATIVE AND VINYLBIOTIN DERIVATIVE 株式会社トクヤマ 2024-04-18 WO disclosed
CN-117024354-B Preparation method of Rui Mi Buti Ni 天津凯莱英制药有限公司 2023-12-08 CN disclosed
CN-117024354-A Preparation method of Rui Mi Buti Ni 天津凯莱英制药有限公司 2023-11-10 CN disclosed
US-20130142886-A1 COMPOSITIONS OF DIBROMOMALANOMIDE AND THEIR USE AS BIOCIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
EP-2582238-A1 COMPOSITIONS OF DIBROMOMALONAMIDE AND THEIR USE AS BIOCIDES Dow Global Technologies LLC (US) 2013-04-24 EP disclosed
WO-2013037626-A1 ISOTHIAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2013-03-21 WO disclosed
WO-2012021340-A1 COMPOSITIONS OF DIBROMOMALONAMIDE AND THEIR USE AS BIOCIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2012-02-16 WO disclosed
EP-1802590-A1 SUBSTITUTED N-ALKYLPYRIMIDINONES Pharmacia & Upjohn Company LLC (US) 2007-07-04 EP disclosed
WO-2006040666-A1 SUBSTITUTED N-ALKYLPYRIMIDINONES PHARMACIA & UPJOHN COMPANY LLC (US) 2006-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130142886-A1 COMPOSITIONS OF DIBROMOMALANOMIDE AND THEIR USE AS BIOCIDES DDT, BCHE, MGAM ALDH1A1 1719/4885KDM4E 2395/4885HPGD 3102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.